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Development of tight junctions between odontoblasts in early dentinogenesis as revealed by freeze-fracture
(Wiley-Blackwell, 1997-07-01)
Background: Mature odontoblasts possess junctional structures constituted by adherens, gap, and tight junctions. Although adherens and gap junctions appear early between odontoblasts, there is no information on the appearance ...
A New CRB1 Rat Mutation Links Müller Glial Cells to Retinal Telangiectasia
(Society for Neuroscience, 2015-04)
Wehave identified and characterized a spontaneousBrownNorwayfrom Janvier rat strain (BN-J) presenting a progressive retinal degeneration
associated with early retinal telangiectasia, neuronal alterations, and loss of ...
Metformin inhibition of colorectal cancer cell migration is associated with rebuilt adherens junctions and FAK downregulation
(Wiley, 2020-04-02)
E‐cadherin, a central component of the adherens junction (AJ), is a single‐pass trans- membrane protein that mediates cell?cell adhesion. The loss of E‐cadherin surface ex- pression, and therefore cell?cell adhesion, leads ...
Sertoli–immature spermatids disengagement during testis regression in the armadillo
(BioScientifica, 2019-01)
In nature, mammalian seasonal breeders undergo spermatogenetic arrest during the non-breeding season. In the large hairy armadillo Chaetophractus villosus, testis regression initiates with immature post-meiotic germ cells ...
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly
(Facultad de Medicina y CienciaCentro de Biología Celular y Biomedicina CEBICEM, 2019)
The permeability of endothelial cells is regulated by the stability of the adherens junctions, which is highly sensitive to kinase-mediated phosphorylation and endothelial nitric oxide synthase (eNOS)-mediated S-nitrosylation ...
Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders : a novel perspective on congenital Zika syndrome
(2019-08)
Radial glial cells (RGCs) are the neural stem/progenitor cells (NSPCs) that give rise to most of neurons and glial cells that constitute the adult central nervous system. A hallmark of RGCs is their polarization along the ...
Disruption of cdh2/n-cadherin-based adherens junctions leads to apoptosis of ependymal cells and denudation of brain ventricular wallsJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGYJ NEUROPATH EXP NEUROL
(ASSOCIATION OF THE JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2013)
Disruption of cdh2/n-cadherin-based adherens junctions leads to apoptosis of ependymal cells and denudation of brain ventricular wallsJOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGYJ NEUROPATH EXP NEUROL
(ASSOCIATION OF THE JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2013)
First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells
(PeerJ Inc, 2021-05-27)
Background: Adherens junctions (AJ) are involved in cancer, infections and neurodegeneration. Still, their composition has not been completely disclosed. Poly(ADP-ribose) polymerases (PARPs) catalyze the synthesis of ...