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Polyautoimmunity and familial autoimmunity in systemic sclerosis
Characterization of the extent to which particular combinations of autoimmune diseases occur in excess of that expected by chance may offer new insights into possible common pathophysiological mechanisms. The goal of this ...
Autoimmune vitiligo in rheumatic disease in the mestizo Mexican population
(Spandidos Publications, 2016-06-01)
Vitiligo is a chronic disease characterized
by the dysfunction or destruction of melanocytes with
secondary depigmentation. The aim of the present study
was to determine the prevalence of vitiligo associated with
autoimmune ...
The role of regulatory T Cells in autoimmune orchitis
(Wiley Blackwell Publishing, Inc, 2018-12)
Regulatory T cells (Tregs) mediate tolerance to self-antigens maintaining immune homeostasis. Defects in the number and function of Tregs lead to aberrant immune responses to autologous components, thereby causing autoimmune ...
Common mechanisms of autoimmune diseases (the autoimmune tautology)
The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms and genetic factors has been called autoimmune tautology, and indicates that they have a common origin. The autoimmune phenotypes vary ...
Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. For many years, researchers in the field of autoimmunity have focused on the role of the immune components in the etiopathogenesis of autoimmune diseases. However, some studies have demonstrated the ...
Neuroimmunomodulatory interactions in the genesis and outcome of autoimmune disease
(Karger Publishers, 2018)
Introducing polyautoimmunity: secondary autoimmune diseases no longer exist
(Universidad del Rosario, 2012)
Similar pathophysiological mechanisms within autoimmune diseases have stimulated searches for common genetic roots. Polyautoimmunity is defined as the presence of more than one autoimmune disease in a single patient. When ...