Buscar
Mostrando ítems 31-40 de 151
HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens
(Cell Press, 2021-07)
Humanity is currently facing the challenge of two devastating pandemics caused by two very different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which has swept the world in the course of a ...
Molecular Recognition of Surface Trans-Sialidases in Extracellular Vesicles of the Parasite Trypanosoma cruzi Using Atomic Force Microscopy (AFM)
(2022-06-28)
Trans-sialidases (TS) are important constitutive macromolecules of the secretome present on the surface of Trypanosoma cruzi (T. cruzi) that play a central role as a virulence factor in Chagas disease. These enzymes have ...
Single domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge
(American Society for Microbiology, 2014-05)
Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NAspecific single-domain antibodies (N1-VHHm) and evaluated their in vitro and in vivo antiviral ...
Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein
(BMJ Publishing Group, 2020-06)
Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor immunity. They express NKG2D, an activating receptor that promotes tumor elimination through recognition of the MHC class I chain-related ...
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
(Nature Publishing Group, 2009)
Unusual naturally occurring humoral and cellular mutated epitopes of hepatitis B virus in a chronically infected argentine patient with anti-HBs antibodies
(American Society for Microbiology, 2006-06)
Serum hepatitis B virus (HBV) DNA was extracted from a chronically infected patient with cocirculation of hepatitis B surface antigen (HBsAg) and anti-HBs antibodies. Direct PCR and clone-derived sequences of the S and ...
Fate of Neospora-seropositive animals: An opinion
(Sociedad Chilena de Parasitología, 2005)
Restitución de la inmunidad antitumoral a partir de la generación de anticuerpos contra MICARestitution of antitumor immunity through the generation of antibodies against MICA
(2019-05-06)
Vencer el escape inmune del tumor y erradicar los tumores y metástasis constituye un desafío en inmuno-oncología. Las células T CD8+ citotóxicas y las citotóxicas naturales (células NK) son jugadores importantes en la ...