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Chronic Recurrent Multifocal Osteomyelitis Primarily Affecting the Spine Treated With Anti-TNF Therapy
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Study Design. A case report describing chronic recurrent multifocal osteomyelitis (CRMO) with initial presentation limited to spine, successfully treated by anti-TNF-alpha therapy after failure of conventional treatment ...
Thalidomide analogues: Tumor necrosis factor-alpha inhibitors and their evaluation as anti-inflammatory agents
(Elsevier Science, 2016-02)
A series of related thalidomide derivatives (2-9) were synthesized by microwave irradiation and evaluated for anti-inflammatory activity. Such activity was assessed in vivo and ex vivo. Compounds 2, 8 and 9 showed the ...
Late response to anti-TNF-alpha therapy in refractory mucocutaneous lesions of Beh double dagger et`s disease
(SPRINGER HEIDELBERG, 2011)
Beh double dagger et`s disease (BD) is a multisystem chronic inflammatory disorder characterized by oral and genital ulceration and ocular involvement. Recurrent oral and genital ulcers are the most common symptoms of BD ...
Multiple imputation procedures allow the rescue of missing data: An application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy
(Sociedad de Biología de Chile, 2005)
Longitudinal studies aimed at evaluating patients clinical response to specific therapeutic treatments are frequently summarized in incomplete datasets due to missing data. Multivariate statistical procedures use only ...
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis
(2016-09-01)
TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative ...
Changes in the TNF-alpha/IL-10 ratio in hyperglycemia-associated pregnancies
(Elsevier B.V., 2015-03-01)
Aims: TNF-alpha is a diabetogenic cytokine associated with adverse outcomes during pregnancy that can be counterbalanced by IL-10. We have investigated IL-10 and TNF-alpha balance at maternal and placental levels in ...