Buscar
Mostrando ítems 31-40 de 663
Efeitos e mecanismos da privação alimentar sobre o metabolismo mitocondrial de Caenorhabditis elegans
(Universidade Federal de São Paulo, 2022-02-22)
Introduction: Dietary deprivation was one of the most frequent evolutionary
pressures. Because of that, living organisms developed complex mechanisms to
survive those challenges. Mitochondria are dynamic organelles ...
Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
(Amer Assoc Cancer ResearchPhiladelphiaEUA, 2011)
Identificação de alterações estruturais e de vias de sinalização em corações de camundongos Knockout para o receptor Mas de Angiotensina-(1-7)
(Universidade Federal de Minas GeraisUFMG, 2011-07-18)
Angiotensin(Ang)-(1-7) has been widely investigated due to its Ang II opposite effects in different organs. Consequently, Ang-(1-7) represents a potential target for new therapeutic approaches. Taking into consideration ...
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
(Portland Press, 2017-03-07)
Activation of AMP-activated protein kinase (AMPK) in endothelial cells regulates energy homeostasis, stress protection and angiogenesis, but the underlying mechanisms are incompletely understood. Using a label-free ...
Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
(2019-07-01)
Background: Adiponectin exhibits anti-inflammatory actions and is mainly expressed in adipose tissue. However, recent studies have shown that adiponectin can also be secreted by skeletal muscle fibers with autocrine and ...
Thyroid Hormone-Induced Expression of the Hepatic Scaffold Proteins Sestrin2, β-Klotho, and FRS2α in Relation to FGF21-AMPK Signaling
(Georg Thieme Verlag, 2018)
© 2018 J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart New York. Thyroid hormone (3,3′,5-triiodothyronine, T 3) accelerates energy metabolism in the liver through mechanisms involving upregulation of AMP-activated ...
Expressão de AMP-proteína quinase ativada (pAMPK) em adenomas hipofisários removidos cirurgicamente de pacientes com acromegalia
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em NeurociênciasUFMG, 2021-04-05)
Introduction: AMPK (AMP-activated protein kinase) is an enzyme that acts as a metabolic sensor by changing the ATP / AMP ratio and is related to the modulation of cell proliferation. The aim of this work was to study the ...
Fructose-Induced Hypothalamic AMPK Activation Stimulates Hepatic PEPCK and Gluconeogenesis due to Increased Corticosterone Levels
(ENDOCRINE SOCCHEVY CHASE, 2012)
Fructose consumption causes insulin resistance and favors hepatic gluconeogenesis through mechanisms that are not completely understood. Recent studies demonstrated that the activation of hypothalamic 5'-AMP-activated ...