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Expression of heterochromatin protein 1 in the primary tumor of breast cancer patients in the presence or absence of occult metastatic cells in the bone marrow
(WICHTIG EDITORE, 2008)
Gene silencing may occur in breast cancer samples from patients presenting with occult metastatic cells in the bone marrow and one mechanism regulating gene suppression is heterochromatin formation. We have studied whether ...
Positive HER-2 protein expression in circulating prostate cells and micro-metastasis, resistant to androgen blockage but not diethylstilbestrol
(Facultad de Ciencias, 2011)
Introduction : HER-2 expression in prostate cancer is associated with a worse prognosis and is suggested to play a role in androgen resistance. We present a study of HER-2 expression in circulating tumor cells and ...
Impact of gestational low protein diet and postnatal bisphenol A exposure on chemically induced mammary carcinogenesis in female offspring rats
(John Wiley & Sons Inc, 2019-07)
This study evaluated the effect of gestational low protein diet (LPD) and/or postnatal bisphenol A (BPA) exposure on mammary gland development and carcinogenesis in female offspring. Pregnant Sprague-Dawley rats were fed ...
Hypothalamic S1p/s1pr1 Axis Controls Energy Homeostasis
(Nature Publishing Group, 2014)
Análisis del efecto neuroprotector de agonistas de receptores nucleares en modelo farmacológico de Parkinson en neuronas dopaminérgicas.
(Universidad Nacional de Colombia - Sede Bogotá, 2019-12-10)
La enfermedad de Parkinson (EP) es la segunda patología neurodegenerativa más prevalente a nivel mundial se caracteriza por la muerte sistemática de las neuronas de la SNpc, la cual se ha vinculado al estrés oxidativo y ...
Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles
(BioMed Central, 2019-04)
Background: Cancer cells evolve and constitute heterogeneous populations that fluctuate in space and time and are subjected to selection generating intratumor heterogeneity. This phenomenon is determined by the acquisition ...