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Different enzymatic activities in carp (Cyprinus carpio L.) as potential biomarkers of exposure to the pesticide methomyl
(Institute for Medical Research and Occupational Health, 2014)
High-affinity binding of fatty acyl-CoAs and peroxisome proliferator-CoA esters to glutathione S-transferases. Effect on enzymatic activity
(1999)
Acyl-CoAs are present at high concentrations within the cell, yet are strongly buffered lay specific binding proteins in order to maintain a low intracellular unbound acyl-CoA concentration, compatible with their metabolic ...
The effect of sixteen medicinal plants used in the Brazilian pharmacopoeia on the expression and activity of glutathione S-transferase in hepatocytes and leukemia cells
(TAYLOR & FRANCIS INC, 2009)
Glutathione S-transferase (GST) is a family of enzymes involved in the detoxification of electrophilic compounds. Different classes of GST are expressed in various organs, such as liver, lungs, stomach and others. Expression ...
Glutathione transferase pi (GSTpi) expression in breast cancer: An immunohistochemical and molecular study
(Elsevier Gmbh, Urban & Fischer Verlag, 2012-01-01)
Breast cancer is the most frequent cancer in women worldwide. Prognostic markers are important for diagnosis, allowing therapeutic strategies to be defined more efficiently. The expression of the glutathione S-transferase ...
Glutathione transferase pi (GSTpi) expression in breast cancer: An immunohistochemical and molecular study
(Elsevier Gmbh, Urban & Fischer Verlag, 2012-01-01)
Breast cancer is the most frequent cancer in women worldwide. Prognostic markers are important for diagnosis, allowing therapeutic strategies to be defined more efficiently. The expression of the glutathione S-transferase ...
Glutathione-s-transferase modified electrodes for detecting anticancer drugs
(Elsevier B.V., 2014-08-15)
With the fast growth of cancer research, new analytical methods are needed to measure anticancer drugs. This is usually accomplished by using sophisticated analytical instruments. Biosensors are attractive candidates for ...
Is nullity for Glutathione S-transferase genes GSTT1 and GSTM1 protective against leprosy?
(Lepra, 2016-06-01)
Introduction: Leprosy is a slow and progressive infectious disease caused by Mycobacterium leprae. The generation of free radicals called reactive oxygen species (ROS), which promote destruction of the bacillus within ...
Comparative effects of superoxide anion and hydrogen peroxide on microsomal and cytosolic glutathione S-transferase activities of rat liver
(2010)
Glutathione S-transferases (GSTs) are isoenzymes occurring in the cytoplasm and as integral membrane proteins. In addition to their role in drug metabolism by conjugating electrophilic and lipophilic compounds with glutathione ...
Arsenic exposure, profiles of urinary arsenic species, and polymorphism effects of glutathione-s-transferase and metallothioneins
(Elsevier Ltd, 2018)
© 2018 Elsevier Ltd This study assessed the effects of polymorphic variants of gutathione-S-transferase and metallothioneins on profiles of urinary arsenic species. Drinking groundwater from Margarita and San Fernando, ...