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Molecular diagnosis of Chagas' disease and use of an animal model to study parasite tropism
(2003)
Chagas' disease, which is an important health problem in humans, is caused by the protozoan Trypanosoma cruzi. The cellular and molecular mechanisms, involved in the selective tropism of T. cruzi to different organs remain ...
Efeitos do exercício excêntrico na reabilitação do músculo esquelético de camundongos mdx após 3 e 21 dias de treinamento. Avaliações morfológica, funcional e molecular
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Fisioterapia - PPGFtCâmpus São Carlos, 2019-05-16)
Duchenne Muscular Dystrophy (DMD) is a degenerative genetic disease of a recessive nature linked to the mutation of the Xp21 region of the X chromosome. DMD is characterized by the absence of the protein dystrophin, which ...
Assessment of molecular and genetic evolution, antigenicity and virulence properties during the persistence of the infectious bronchitis virus in broiler breeders
(2017-10-01)
The infectious bronchitis virus (IBV) causes a highly contagious disease [infectious bronchitis (IB)] that results in substantial economic losses to the poultry industry worldwide. We conducted a molecular and phylogenetic ...
Molecular characterization, tissue tropism, and genetic variability of the novel Mupapillomavirus type HPV204 and phylogenetically related types HPV1 and HPV63
(Public Library of Science, 2017-04)
HPV204 is the only newly identified Mupapillomavirus (Mu-PV) type in more than a decade. To comprehensively characterize HPV204, we performed a detailed molecular analysis of the viral genome and evaluated its clinical ...
The MHC gene region of murine hosts influences the differential tissue tropism of infecting Trypanosoma cruzi strains.
(Public Library of Science, 2014)
Organs infected with Trypanosoma cruzi and DTU identification in the naturally infected rodent Octodon degus
(Elsevier, 2020)
Chagas disease is a public health problem in America. Its parasite, Trypanosoma cruzi, presents different discrete typing units (DTUs), colonizes organs of mammalian hosts in chronic infections, and presents tropism for ...
The unfolding palette of COVID-19 multisystemic syndrome and its neurological manifestations
(Elsevier, 2021-07)
Although our current knowledge of the pathophysiology of COVID-19 is still fragmentary, the information so far accrued on the tropism and life cycle of its etiological agent SARS-CoV-2, together with the emerging clinical ...