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Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction
(Wiley-VCH Verlag, 2019)
Tau protein is a natively unfolded protein whose primary role is to participate in axonal transport closely associated with microtubules. Neurodegenerative disorders including Alzheimer's disease and Tauopathies involved ...
Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies
(2002)
The intracellular polymerization of cytoskeletal proteins into their supramolecular assemblies raises many questions regarding the regulatory patterns that control this process. Binding experiments using the ELISA solid ...
Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization
(COMPANY OF BIOLOGISTS LTD, 2006-05-15)
The microtubule-associated tau protein participates in the organization and integrity of the neuronal cytoskeleton. A nuclear form of tau has been described in neuronal and non-neuronal cells, which displays a nucleolar ...
Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons
(Academic Press Inc., 2014)
Inhibition of phospholipase A(2) in rat brain decreases the levels of total Tau protein
(SPRINGER WIEN, 2011)
The microtubule-associated protein Tau promotes the assembly and stability of microtubules in neuronal cells. Six Tau isoforms are expressed in adult human brain. All six isoforms become abnormally hyperphosphorylated and ...
Secondary Metabolites in Ramalina terebrata Detected by UHPLC/ESI/MS/MS and Identification of Parietin as Tau Protein Inhibitor
(2016)
Liquid chromatography coupled with mass spectrometry is an outstanding methodology for fast analysis of phenolic compounds in biological samples. Twenty two compounds were quickly and accurately identified in the methanolic ...
Emerging Noninvasive Biomarkers for Early Detection of Alzheimer's Disease
(2012)
Alzheimer's disease (AD) diagnosis still depends on the triad of clinical, imaging and neuropsychological testing. The development of accurate, easy to use and inexpensive biological markers for AD is a long-standing ...
Neuroimmune tau mechanisms: their role in the progression of neuronal degeneration
(MDPI, 2018-04)
Progressive neurodegenerative pathologies in aged populations are an issue of major concern worldwide. The microtubule-associated protein tau is able to self-aggregate to form abnormal supramolecular structures that include ...