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MOTIONAL PROPERTIES OF SPIN LABELS IN PROTEINS - EFFECTS OF HYDRATION
(Natl Research Council Canada, 1986-02-01)
Characterization of a conformationally sensitive TOAC spin-labeled substance P
(Elsevier B.V., 2008-11-01)
To probe the binding of a peptide agonist to a G-protein coupled receptor in native membranes, the spin-labeled amino acid analogue 4-amino-4-carboxy-2,2,6,6-tetramethyl-piperidino-1-oxyl (TOAC) was substituted at either ...
Comparative EPR and fluorescence conformational studies of fully active spin-labeled melanotropic peptides
(Elsevier B.V., 2001-05-25)
Similar to melanocyte stimulating hormone (alpha -MSH), its potent and long-acting analogue, [Nle(4), D-Phe(7)]alpha -MSH, when labeled with the paramagnetic amino acid probe 2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino- ...
Using Genetically Encodable Self-Assembling GdIIISpin Labels To Make In-Cell Nanometric Distance Measurements
(Wiley VCH Verlag, 2016-09)
Double electron–electron resonance (DEER) can be used to study the structure of a protein in its native cellular environment. Until now, this has required isolation, in vitro labeling, and reintroduction of the protein ...
Síntese e estudos biológicos conformacionais e enzimáticos de análogos da angiotensina I contendo marcador de spin toac
(Universidade Federal de São Paulo (UNIFESP), 2007)
Este trabalho iniciou um estudo conjugado abrangendo o enzimático com o de ressonância paramagnética eletrônica (RPE) de substratos peptídicos marcados paramagneticamente. A enzima conversora de angiotensina I (ECA, EC ...
Síntese e estudos enzimáticos e conformacionais de análogos da angiotensina I e da bradicinina contendo marcador de Spin Toc
(Universidade Federal de São Paulo (UNIFESP), 2011)
O presente projeto procurou investigar os peptideos vasoativos angiotensina I (AI) e bradicinina (BK) como substratos da enzima conversora da angiotensina I (ECA), lancando-se mao da marcacao dos mesmos com um derivado de ...
Alternative and simple normal-phase HPLC enantioseparation of a chiral amino acid-type spin label derivative
(Sociedade Brasileira de Química, 2013)
Conformational basis for the biological activity of TOAC-labeled angiotensin II and bradykinin: Electron paramagnetic resonance, circular dichroism, and fluorescence studies
(2004-08-05)
N-Terminally and internally labeled analogues of the hormones angiotensin (AII, DRVYIHPF) and bradykinin (BK, RPPGFSPFR) were synthesized containing the paramagnetic amino acid 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4- ...
Conformational basis for the biological activity of TOAC-labeled angiotensin II and bradykinin: Electron paramagnetic resonance, circular dichroism, and fluorescence studies
(2004-08-05)
N-Terminally and internally labeled analogues of the hormones angiotensin (AII, DRVYIHPF) and bradykinin (BK, RPPGFSPFR) were synthesized containing the paramagnetic amino acid 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4- ...