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Impact of sphingomyelin acyl chain (16:0 vs 24:1) on the interfacial properties of Langmuir monolayers: a PM-IRRAS study
(Elsevier Science, 2019-01)
Membrane structure is a key factor for the cell`s physiology, pathology, and therapy. Evaluating the importance of lipid species such as N-nervonoyl sphingomyelin (24:1-SM) —able to prevent phase separation— to membrane ...
Changes in biophysical properties of membranes containing sphingomyelins with very long chain PUFA during cooling
(Sociedad Argentina de Biofísica, 2019)
Although the molecular changes that affect the spermatozoa of economically important animals, such as bull and ram, are of great research interest, changes regarding plasma membrane lipid organization as temperature decreases ...
Structural insights into substrate binding of brown spider venom class ii phospholipases d
(2015-09-01)
Phospholipases D (PLDs), the major dermonecrotic factors from brown spider venoms, trigger a range of biological reactions both in vitro and in vivo. Despite their clinical relevance in loxoscelism, structural data is ...
Tryptophan and aspartic acid residues present in the glycerophosphoryl diester phosphodiesterase (GDPD) domain of the Loxosceles laeta phospholipase D are essential for substrate recognition
(PERGAMON-ELSEVIER SCIENCE LTD, 2014)
It is known that the family of phospholipases D (PLD) from spiders of the genus Loxosceles, hydrolyze the substrates sphingomyelin and lisophosphatidylcholine, by their catalytic acid-base action which involves two histidines. ...
Long-term biopermanence of ceramides, cholesteryl esters, and ether-linked triglycerides with very-long-chain PUFA in the cadmium-damaged testis
(Elsevier Science, 2014-01)
Cadmium is known to harm rat testis by causing the dose-dependent apoptotic or necrotic death of seminiferous epithelium cells. Here we investigated how this affects the lipids with long-chain (C18-C22) and very-long-chain ...
Differentiation-related changes in lipid classes with long-chain and very long-chain polyenoic fatty acids in rat spermatogenic cells
(American Society for Biochemistry and Molecular Biology, 2010-10)
In rat seminiferous tubules (ST), cells that contain polar and neutral lipids with long-chain polyenoic fatty acids (PUFA) and sphingomyelins (SM) and ceramides (Cer) with very long chain (VLC) PUFA of the n-6 series ...
Sphingomyelin composition and physical asymmetries in native acetylcholine receptor-rich membranes
(Springer, 2002-12)
Selective enzymatic hydrolysis, lipid compositional analyses, and fluorescence studies have been carried out on acetylcholine receptor (AChR)-rich membranes from Torpedinidae to investigate the topology of sphingomyelin ...
Membrane Restructuring Events during the Enzymatic Generation of Ceramides with Very Long-Chain Polyunsaturated Fatty Acids
(American Chemical Society, 2018-04)
In rat sperm heads, sphingomyelin (SM) species that contain very long-chain polyunsaturated fatty acid (V-SM) become ceramides (V-Cer) after inducing in vitro the acrosomal reaction. The reason for such a specific location ...