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SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes
(2012)
Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance cancer cells malignancy. In the present study, we analysed the role of ...
Influence of cheese making technologies on plasmin and coagulant associated proteolysis
(Elsevier Science, 2015-06)
The aim of this work was to study the influence of different cheese-making technologies applied for three varieties of Argentinean cheeses on the action of coagulant enzyme, plasmin-plasminogen system and proteolysis. For ...
Altered endothelial function following the Fontan procedure
(CAMBRIDGE UNIV PRESS, 2008)
Objective: Thrombosis has been widely described after the Fontan procedure. The vascular endothelium plays a central role in the control of coagulation and fibrinolysis. The aim of this study was to investigate if patients ...
Plasminogen hydrolysis by cathepsin S and identification of derived peptides as selective substrate for cathepsin V and cathepsin L inhibitor
(Walter de Gruyter Gmbh, 2010-05-01)
Plasminogen is a glycoprotein implicated in angiogenesis and fibrin clot degradation associated with the release of angiostatin and plasmin activation, respectively We have recently reported that cathepsin V. but not ...
Effects of short-term l-arginine supplementation on lipid profile and inflammatory proteins after acute resistance exercise in overweight men
(2014-01-01)
Background & aim: Dyslipidemia is involved with in development of cardiovascular diseases and obesity, exercise is recommended as a successful intervention. Dietary l-arginine (l-arg) supplementation may improve in lipid ...
The Vampirome: Transcriptome and proteome analysis of the principal and accessory submaxillary glands of the vampire bat Desmodus rotundus, a vector of human rabies
(2013-04-06)
Vampire bats are notorious for being the sole mammals that strictly feed on fresh blood for their survival. While their saliva has been historically associated with anticoagulants, only one antihemostatic (plasminogen ...
The Vampirome: Transcriptome and proteome analysis of the principal and accessory submaxillary glands of the vampire bat Desmodus rotundus, a vector of human rabies
(2013-04-06)
Vampire bats are notorious for being the sole mammals that strictly feed on fresh blood for their survival. While their saliva has been historically associated with anticoagulants, only one antihemostatic (plasminogen ...
The effect of thyroid hormones on the white adipose tissue gene expression of PAI-1 and its serum concentration
(Associação Brasileira de Divulgação Científica, 2009-12-01)
Metabolic syndrome is associated with an increased risk of developing cardiovascular diseases and Plasminogen activator inhibitor 1 (PAI-1) overexpression may play a significant role in this process. A positive correlation ...