Buscar
Mostrando ítems 21-30 de 1443
Effect of phosphoric acid on the degradation of human dentin matrix
(2013-01-01)
This study determined if dentin proteases are denatured by phosphoric acid (PA) used in etch-and-rinse dentin adhesives. Dentin beams were completely demineralized with EDTA for 30 days. We acid-etched experimental groups ...
Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors
(2021-08-02)
The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and public health systems throughout the world. In recent years, peptide-based therapeutics have been widely studied and developed to treat ...
IAF, QGF, and QDF peptides exhibit cholesterol-lowering activity through a statin-like HMG-CoA reductase regulation mechanism: In silico and in vitro approach
(2021-10-01)
In this study, in silico approaches are employed to investigate the binding mechanism of peptides derived from cowpea β-vignin and HMG-CoA reductase. With the obtained information, we designed synthetic peptides to evaluate ...
Validation of a Phage Display Method for Protease Inhibitor Selection Using SFTI and HiTI Synthetic Hybrid Peptides
(Bentham Science Publ Ltd, 2010-11-01)
A recombinant Haematobia irritans irritans trypsin inhibitor (HiTI - Mw 7030 kDa) phagemid library was constructed and displayed functionally on the tip of the filamentous M13 phage. A combinatorial library of 7.2 x 10(6) ...
Peptides from CcdB protein as novel inhibitors of DNA gyrase
(John Wiley & Sons Ltd, 2008-08-01)
Molecular modeling, design and structural studies of a new class of peptide inhibitors of bacterial topoisomerases
(John Wiley & Sons Ltd, 2010-09-01)
Molecular modeling, design and structural studies of a new class of peptide inhibitors of bacterial topoisomerases
(John Wiley & Sons Ltd, 2010-09-01)
Peptides from CcdB protein as novel inhibitors of DNA gyrase
(John Wiley & Sons Ltd, 2008-08-01)
Peptides from yacg protein as inhibitors of DNA gyrase and human topoisomerase II alpha
(Wiley-Blackwell, 2014-09-01)