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Auditorío Podcast
(Universidad Católica Boliviana "San Pablo" - IUC VLIR-UOS., 2020)
A dominant function of p38 mitogen-activated protein kinase signaling in receptor activator of nuclear factor-kappa B ligand expression and osteoclastogenesis induction by Aggregatibacter actinomycetemcomitans and Escherichia coli lipopolysaccharide
(Blackwell Publishing, 2008-04-01)
Background and Objective: Lipopolysaccharide from gram-negative bacteria is one of the microbial-associated molecular patterns that initiate the immune/inflammatory response, leading to the tissue destruction observed in ...
Melatonin attenuates Her-2, p38 MAPK, p-AKT, and mTOR levels in ovarian carcinoma of ethanol-preferring rats
(2014)
Epidermal growth factor receptors 2 (Her-2) and 4 (Her-4) are closely associated with ovarian cancer (OC) progression and metastasis, and a more complete understanding of these signaling pathways allow the development of ...
EL PAPEL DE LA MAP CINASA p38 EN LA REGULACIÓN DEL INFLAMASOMA EN MACRÓFAGOS SUSCEPTIBLES Y RESISTENTES A LA TOXINA LETAL DE BACILLUS ANTHRACIS
(2011-06-17)
The inflammasome is a multiprotein complex that controls activation of caspase-1 and proinflammatory
cytokine production in response to different pathogens or intracellular
components released in response to cell damage. ...
Systematic review of p38 mitogen-activated kinase and its functional role in reproductive tissues
(2018-01-01)
Oxidative stress (OS) plays a role in uterine tissue remodeling during pregnancy and parturition. While p38 MAPK is an OS-response kinase, a precise functional role is unknown. Therefore, we conducted a systematic review ...
Requirement for epithelial p38α in KRAS-driven lung tumor progression
(National Academy of Sciences, 2020-02)
Malignant transformation entails important changes in the control of cell proliferation through the rewiring of selected signaling pathways. Cancer cells then become very dependent on the proper function of those pathways, ...
High glucose concentration stimulates NHE-1 activity in distal nephron cells: the role of the Mek/Erk1/2/p90RSK and p38MAPK signaling pathways
(Basel, 2014)
AIMS:
In models of diabetes, distal nephron cells contribute to glucose uptake and oxidation. How these cells contribute to the use of glucose for the regulation of H(+) extrusion remains unknown. We used Madin-Darby ...