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The isoflavone genistein enhances osteoblastogenesis: signaling pathways involved
(Springer, 2020-01-02)
Phytoestrogens have been proposed as a natural therapy for prevention of bone loss. In this work, we studied the mechanism of action of genistein on osteoblast differentiation. Primary cell cultures of calvarial osteoblasts ...
Phytocystatin CsinCPI-2 Reduces Osteoclastogenesis and Alveolar Bone Loss
(2022-02-01)
Periodontal disease (PD) is a polymicrobial chronic inflammatory condition of the supporting tissues around the teeth, leading to the destruction of surrounding connective tissue. During the progression of PD, osteoclasts ...
Differential cytokine expressions affect the severity of peri-implant disease
(Wiley-blackwell Publishing, IncMaldenEUA, 2009)
Osteocyte Alterations Induce Osteoclastogenesis in an In Vitro Model of Gaucher Disease
(Molecular Diversity Preservation International, 2017-01)
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid ...
Osteocyte alterations induce osteoclastogenesis in an in vitro model of gaucher disease
(MDPI AG, 2017-01)
Gaucher disease (GD) is caused by mutations in the glucosylceramidase β (GBA 1) gene that confer a deficient level of activity of glucocerebrosidase (GCase). This deficiency leads to the accumulation of the glycolipid ...
Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in
(Wiley, 2016)
The main oxygen sensor hypoxia inducible factor (HIF) prolyl hydroxylase 2 (PHD2) is a critical regulator of tissue homeostasis during erythropoiesis, hematopoietic stem cell maintenance, and wound healing. Recent studies ...
Cementoblast gene expression is regulated by Porphyromonas gingivalis lipopolysaccharide partially via Toll-like receptor-4/MD-2
(Int Amer Assoc Dental Researchi A D R/a A D RAlexandriaEUA, 2004)
Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling
(Nature, 2021)
Particulate autologous tooth roots are increasingly used for alveolar bone augmentation; however, the proteomic profile of acid dentin lysate and the respective cellular response have not been investigated. Here we show ...