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Identification of New Snake Venom Metalloproteinase Inhibitors Using Compound Screening and Rational Peptide Design
(2012)
The majority of snakebite envenomations in Central America are caused by the viperid species Bothrops asper, whose venom contains a high proportion of zinc-dependent metalloproteinases that play a relevant role in the ...
Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling
(ELSEVIER SCIENCE BV, 2010)
Structural vascular changes in two-kidney, one-clip (2K-1C) hypertension may result from increased matrix metalloproteinase (MMP)-2 activity. MMP-2 activation is regulated by other MMPs, including transmembrane-MMPs, and ...
Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters in gingival crevicular fluid from periodontitis-affected patients
(2005)
Background: The aim of this work was to improve the assessment of the
periodontal disease status through measurements of extracellular matrix
metalloproteinases (MMPs) and their tissular inhibitors (TIMPs) in the ...
Inhibitors of human collagenase, MMP1
(2009-01-01)
Different common drugs (Meloxicam, Tenoxicam and Piroxicam, and sodium alendronate) were tested both experimental and theoretically as inhibitors of interstitial human collagenase, also known as matrix metalloproteinase 1 ...
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease
(Elsevier, 2017-02)
The most important regulators of tissue remodelling during ovarian follicular growth, development, ovulation and atresia are gonadotropins, steroid hormones, growth factors and different proteolytic enzymes. Matrix ...
Finasteride treatment alters MMP-2 and-9 gene expression and activity in the rat ventral prostate
(Wiley-blackwellHobokenEUA, 2010)
Comprehensive Evaluation of the Effects of Enalapril on Matrix Metalloproteinases Levels in Hypertension
(SpringerDordrecht, 2012)
Increased acinar damage of salivary glands of patients with Sjogren's syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3/tissue inhibitor of metalloproteinases 1 and matrix metalloproteinase 9/tissue inhibitor of metalloproteinases 1 ratios
(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2005-09)
Objective. Previous findings in labial salivary glands (LSGs) from patients with Sjogren ' s syndrome (SS) suggest that increased activity and expression of matrix metalloproteinase 9 (MMP-9) and MMP-3 trigger the destruction ...