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In vitro and in vivo activity of benzocphenanthridines against Leishmania amazonensis
(Georg Thieme Verlag, 2014)
Seven benzo[c]phenanthridines, synthetic or isolated from Zanthoxylum rhoifolium root bark, were evaluated against Leishmania amazonensis axenic amastigotes. Five of them were considered leishmanicidal, with IC50 values ...
Metodologia de ensino jigsaw em disciplina de química medicinal
(Sociedade Brasileira de Química, 2013)
In this paper, we describe an educational experience involving the use of the jigsaw method on the Medicinal Chemistry course at the University of São Paulo, Brazil. The goal of this proposal was to investigate acceptance ...
Planejamento de fármacos, biotecnologia e química medicinal: Aplicações em doenças infecciosas
(2010-12-21)
Current drug design strategies are based on the understanding of the physiopathology of diseases, biochemical pathways and selection of molecular targets. Modern biotechnological tools have provided valuable information ...
Natural products from Brazilian biodiversity as a source of new models for medicinal chemistry
(Int Union Pure Applied Chemistry, 2014)
Metodologia de ensino jigsaw em disciplina de química medicinal
(Sociedade Brasileira de Química, 2015)
Síntese de novos derivados triazólicos e avaliação de suas atividades antifúngicas
(Universidade Federal de Minas GeraisBrasilICX - DEPARTAMENTO DE QUÍMICAPrograma de Pós-Graduação em QuímicaUFMG, 2019-08-20)
In the last three decades, the mortality rate caused by fungal infections has substantially increased due the appearance of new pathogenic fungi and the emergence of infections resistant to the available drugs for treatment. ...
Effect of ursolic acid from epicuticular waxes of jacaranda decurrens on schizaphis graminum
(1992)
Ursolic acid from Jacaranda decurrens showed toxicity and feeding deterrency towards the greenbug Schizaphis graminum. Biological activity was determined by analyzing ursolic acid effects on the survival, reproductive ...
CHEMISTRY BEHIND DRUGS DISTRIBUTED BY THE POPULAR PHARMACY PROGRAM IN BRAZIL: SYNTHETIC ROUTES, STRUCTURE-ACTIVITY RELATIONSHIP AND FUTURE PERSPECTIVESA QUÍMICA POR TRÁS DOS MEDICAMENTOS DISTRIBUÍDOS PELO PROGRAMA FARMÁCIA POPULAR NO BRASIL: ROTAS SINTÉTICAS, RELAÇÃO ESTRUTURA-ATIVIDADE E PERSPECTIVAS FUTURAS
(2021-01-01)
Certainly, most chemistry students, patients or simply curious, have already questioned themselves about certain medications present in their daily lives, trying to understand how they work and even how they can be obtained. ...