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Mostrando ítems 21-30 de 100
Análise de polimorfismos dos genes da rota quinurenina em pacientes com meningite bacteriana.
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Genética e Biologia MolecularGenética e Biologia Molecular, 2008-03-28)
Bacterial meningitis (BM) is still an important infectious disease causing death and disability. Invasive bacterial infections of the central nervous systems (CNS) generate some of the most powerful ...
Envolvimento da via da quinurenina na retirada do etanol: evidências comportamentais e bioquímicas
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOQUÍMICA, 2020-10-30)
Anxiety and depression are symptoms associated with ethanol withdrawal that lead
individuals to relapse. In the tryptophan pathway, the enzyme indoleamine 2,3 dioxygenase
(IDO) is responsible for converting tryptophan ...
A First Plasmodium vivax Natural Infection Induces Increased Activity of the Interferon Gamma-Driven Tryptophan Catabolism Pathway
(Frontiers Research Foundation, 2023)
High concentrations of the melatonin metabolite, N-1-acetyl-N (2)-formyl-5-methoxykynuramine, in cerebrospinal fluid of patients with meningitis: a possible immunomodulatory mechanism
(Blackwell Publishing, 2005-10-01)
We evaluated the presence of the melatonin metabolite N-1-acetyl-N-2-formyl-5-methoxykynuramine (AFMK), in cerebrospinal fluid (CSF) of patients with viral meningitis (n = 20) and control samples (n = 8) and correlate AFMK ...
Water Extract from Inflorescences of Industrial Hemp Futura 75 Variety as a Source of Anti-Inflammatory, Anti-Proliferative and Antimycotic Agents: Results from In Silico, In Vitro and Ex Vivo Studies
(MDPI, 2020-05)
Industrial hemp (Cannabis sativa) is traditionally cultivated as a valuable source of fibers and nutrients. Multiple studies also demonstrated antimicrobial, anti-proliferative, phytotoxic and insecticide effects of the ...
Melatonin and its kynurenin-like oxidation products affect the microbicidal activity of neutrophils
(Elsevier B.V., 2006-02-01)
Activated phagocytes oxidize the hormone melatonin to N-1-acethyl-N-2-formyl-5-methoxykynuramine (AFMK) in a superoxide anion- and myeloperoxidase-dependent reaction. We examined the effect of melatonin, AFMK and its ...
Melatonin and its kynurenin-like oxidation products affect the microbicidal activity of neutrophils
(Elsevier B.V., 2006-02-01)
Activated phagocytes oxidize the hormone melatonin to N-1-acethyl-N-2-formyl-5-methoxykynuramine (AFMK) in a superoxide anion- and myeloperoxidase-dependent reaction. We examined the effect of melatonin, AFMK and its ...