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Histone methylations in the developing central nervous system and in neural tube defects
(De Gruyter, 2018-05)
Understanding central nervous system genesis is of crucial relevance to decode different human diseases such as microcephaly or neural tube defects, which arise from incorrect developmental processes. Epigenetic mechanisms ...
Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos
(2013-02-01)
Summary Trichostatin A (TSA) is a histone deacetylase inhibitor that induces histone hyperacetylation and increases gene expression levels. The aim of the present study was to establish a suitable condition for the use of ...
Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos
(2013-02-01)
Summary Trichostatin A (TSA) is a histone deacetylase inhibitor that induces histone hyperacetylation and increases gene expression levels. The aim of the present study was to establish a suitable condition for the use of ...
Trypanosoma cruzi bromodomain factor 2 (BDF2) binds to acetylated histones and is accumulated after UV irradiation
(Elsevier B.V., 2009-05-01)
Histone tail post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination and ADP-ribosylation) regulate many cellular processes. Among these modifications, phosphorylation, methylation and ...
Oxygen tension affects histone remodeling of in vitro-produced embryos in a bovine model
(Elsevier B.V., 2015-06-01)
In vitro production of bovine embryos is a biotechnology of great economic impact. Epigenetic processes, such as histone remodeling, control gene expression and are essential for proper embryo development. Given the ...
K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts
(Elsevier, 2010-04)
Covalent modifications of histones play a role in regulating telomere attrition and cellular senescence. Biotinylation of lysine (K) residues in histones, mediated by holocarboxylase synthetase (HCS), is a novel diet-dependent ...
Histone modifications related to chromosome silencing and elimination during male meiosis in Bengalese finch
(Springer Verlag Berlín, 2014-06)
We report here that a germline-restricted chromosome (GRC) is regularly present in males and females of the Bengalese finch (Lonchura domestica). While the GRC is euchromatic in oocytes, in spermatocytes this chromosome ...
Expression of non-acetylatable lysines 10 and 14 of histone H4 impairs transcription and replication in Trypanosoma cruzi
(P.T. LoVerde, K.R. Matthews, M. Parsons, A.P. Waters, 2016)