Buscar
Mostrando ítems 21-30 de 783
Sesquiterpene Lactones with Anti-Hepatitis C Virus Activity Using Molecular Descriptors
(BENTHAM SCIENCE PUBL LTDSHARJAH, 2012)
Hepatitis C is a worldwide public health problem. The available therapies are limited by their partial effectiveness and with meaningful side-effects. Sesquiterpene lactones (SLs) are a group of natural products with a ...
In vitro inhibition of the hepatic S-oxygenation of the anthelmintic albendazole by the natural monoterpene thymol in sheep
(Taylor & Francis Ltd, 2019-08)
Combinations of bioactive phytochemicals with synthetic compounds have been suggested as promissory tools for the improvement of nematode control in livestock. Bioactive phytochemicals may interfere with the activity of ...
Ingestão proteica na encefalopatia hepática: panorama atual
(2014)
Hepatic encephalopathy is a severe complication of cirrhosis and comprises a complex and multifactorial pathophysiology. However, ammonia exchange between different tissues still deserves attention in relation to neurological ...
Pharmacokinetics of the antimicrobial drug Sulfanilamide is altered in a preclinical model of vascular calcification
(Wiley Blackwell Publishing, Inc, 2017-12)
In vascular smooth muscle, calcium overload is linked to advancing age. The pharmacokinetics of Sulfanilamide (SA), a compound with antibacterial properties, was evaluated in a preclinical model of vascular calcification. ...
Aflatoxin B-1-induced hepatic steatosis: role of carbonyl compounds and active diols on steatogenesis
(Lancet LtdLondonInglaterra, 1999)
Hepatitis C virus in vitro replication is efficiently inhibited by acridone Fac4
(2017-07-01)
Hepatitis C virus (HCV) affects about 170 million people worldwide. The current treatment has a high cost and variable response rates according to the virus genotype. Acridones, a group of compounds extracted from natural ...
Fructose-Induced Hypothalamic AMPK Activation Stimulates Hepatic PEPCK and Gluconeogenesis due to Increased Corticosterone Levels
(ENDOCRINE SOCCHEVY CHASE, 2012)
Fructose consumption causes insulin resistance and favors hepatic gluconeogenesis through mechanisms that are not completely understood. Recent studies demonstrated that the activation of hypothalamic 5'-AMP-activated ...