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The overlooked significance of plasma volume for successful adaptation to high altitude in Sherpa and Andean natives
(National Academy of Sciences, 2019)
In contrast to Andean natives, high-altitude Tibetans present with a lower hemoglobin concentration that correlates with reproductive success and exercise capacity. Decades of physiological and genomic research have assumed ...
Hemoglobin Kansas found by electrophoretic diagnosis in Brazil
(Associação Brasileira de Hematologia e Hemoterapia e daSociedade Brasileira de Transplante de Medula Óssea, 2002-03-01)
Hemoglobinas variantes com afinidade anormal ao oxigênio têm sido encontradas em várias partes do mundo. Pela sua afinidade ao oxigênio, estas hemoglobinas variantes têm sido classificadas e 15 variantes com baixa afinidade ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Severe Hemolytic Anemia due to De novo Hemoglobin Sabine in an argentinian newborn: first case in South America
(SCIENCEDOMAIN international, 2015)
Hemoglobin (Hb) Sabine is an unstable Hb variant that causes hemolytic anemia in heterozygous state, with inclusion bodies in the red blood cells (RBC). This hemoglobin is the result of a point mutation at codon 91(CTG)(CCG) ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis
(Elsevier B. V., 2015)
Hydration-dependent conformational states of hemoglobin. Equilibrium and kinetic behavior
(1990-07-27)
The equilibrium and kinetics of methemoglobin conversion to hemichrome induced by dehydration were investigated by visible absorption spectroscopy. Below about 0.20 g water per g hemoglobin only hemichrome was present in ...
Hydration-dependent conformational states of hemoglobin. Equilibrium and kinetic behavior
(1990-07-27)
The equilibrium and kinetics of methemoglobin conversion to hemichrome induced by dehydration were investigated by visible absorption spectroscopy. Below about 0.20 g water per g hemoglobin only hemichrome was present in ...