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Molecular mechanisms underlying progesterone receptor action in breast cancer: Insights into cell proliferation and stem cell regulation
(Elsevier Science Inc, 2019-12)
The ovarian steroid hormone progesterone and its nuclear receptor, the Progesterone Receptor (PR), play an essential role in the regulation of cell proliferation and differentiation in the mammary gland. In addition, ...
Modeling tumorspheres reveals cancer stem cell niche building and plasticity
(Elsevier Science, 2019-11)
Cancer stem cells have been shown to be critical to the development of a variety of solid cancers. The precise interplay mechanisms between cancer stem cells and the rest of a tissue are still not elucidated. To shed light ...
Nestin+cells forming spheroids aggregates resembling tumorspheres in experimental ENU-induced gliomas
(Histology and Histopathology, 2016)
Integrin α6 (CD49f), the microenvironment and cancer stem cells
(2019)
Cancer is a highly prevalent and potentially terminal disease that affects millions of indi- viduals worldwide. Here, we review the literature exploring the intricacies of stem cells bearing tumori- genic characteristics ...
Cancer stem cell and mesenchymal cell cooperative actions in metastasis progression and hormone resistance in prostate cancer: Potential role of androgen and gonadotropin-releasing hormone receptors (Review)
(Spandidos, 2020)
Prostate cancer (PCa) is the leading cause of male cancer-associated mortality worldwide. Mortality is associated with metastasis and hormone resistance. Cellular, genetic and molecular mechanisms underlying metastatic ...
Analysis of cancer stem cells in dog's mammary neoplasiasAnálise das células tronco tumorais em neoplasias mamárias de cães
(2013-01-01)
Mammary tumors are the most frequent cancers in dogs, representing about 50% of tumors, and have a higher incidence in females of middle aged and elderly. These tumors have been used as a model for breast cancer in women ...
Retina stem cells, hopes and obstacles
(Baishideng Publishing, 2021-10-26)
Retinal degeneration is a major contributor to visual dysfunction worldwide. Although it comprises several eye diseases, loss of retinal pigment epithelial (RPE) and photoreceptor cells are the major contributors to their ...