Buscar
Mostrando ítems 21-30 de 48
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-11-01)
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet ...
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica (ABRADIC), 2001-11-01)
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet ...
P-I class metalloproteinase from Bothrops moojeni venom is a post-proline cleaving peptidase with kininogenase activity: Insights into substrate selectivity and kinetic behavior
(Elsevier B.V., 2014-03-01)
Snake venom metalloproteinases (SVMPs) belonging to P-I class are able to hydrolyze extracellular matrix proteins and coagulation factors triggering local and systemic reactions by multiple molecular mechanisms that are ...
Efeitos bioquímicos e farmacológicos da fosforilação de componentes do sistema calicreínas-cininas
(Universidade Federal de São Paulo (UNIFESP), 2015-11-25)
Phosphorylated kininogen and some of its fragments containing serine phosphorylated bradykinin ([pS6]-Bk) were found in human serum and plasma by phosphoproteomic approaches. In the present study, we report the kininogenase ...
ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity
(Associação Brasileira de Divulgação Científica, 2001-11-01)
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet ...
Heparin affects the interaction of kininogen on endothelial cells
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2011)
In the plasma kallikrein-kinin system, it has been shown that when plasma prekallikrein (PM) and high molecular weight kininogen (HK) assemble on endothelial cells, plasma kallikrein (huPK) becomes available to cleave HK, ...
SUBSTRATE SPECIFICITIES of TISSUE KALLIKREIN and T-KININOGENASE - THEIR POSSIBLE ROLE in KININOGEN PROCESSING
(Amer Chemical Soc, 1992-06-02)
The present studies demonstrate the importance of subsite interactions in determining the cleavage specificities of kallikrein gene family proteinases. the effect of substrate amino acid residues in positions P3-P'3 on the ...