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SPARC induces E-cadherin repression and enhances cell migration through integrin v beta 3 and the transcription factor ZEB1 in prostate cancer cells
(MDPI, 2022)
Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling ...
Expression of laminin-5 and integrins in actinic cheilitis and superficially invasive squamous cell carcinomas of the lip
(ELSEVIER GMBH, URBAN & FISCHER VERLAGJENA, 2012-10)
The progression of carcinogenesis entails the detachment of cells, invasion and migration of neoplastic cells. Alterations in epithelial adhesion and basement membrane proteins might mediate the early stages of carcinogenesis. ...
Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production
(Landes Bioscience, 2014)
Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production
(Landes Bioscience, 2014)
Direct Thy-1/alpha(V)beta(3) integrin interaction mediates neuron to astrocyte communication
(ELSEVIER, 2008-06)
Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a beta(3)-containing integrin in astrocytes to induce tyrosine phosphorylation, RhoA ...
Single-molecule measurements of the effect of force on Thy-1/alpha v beta 3-integrin interaction using nonpurified proteins
(2018)
Thy-1 and alpha v beta 3 integrin mediate bidirectional cell-to-cell communication between neurons and astrocytes. Thy-1/alpha v beta 3 interactions stimulate astrocyte migration and the retraction of neuronal prolongations, ...
Association Between Integrin Expression and Prognosis in Localized Prostate Cancer
(WILEY-LISS, 2010)
BACKGROUND. Integrins and other adhesion molecules are essential for maintaining the epithelial phenotype. Some studies have reported correlations between abnormalities in their expression and carcinogenesis, but their ...
Single-molecule measurements of the effect of force on Thy-1/αvβ3-integrin interaction using nonpurified proteins
(Amer Soc Cell Biology, 2018)
Thy-1 and alpha v beta 3 integrin mediate bidirectional cell-to-cell communication between neurons and astrocytes. Thy-1/alpha v beta 3 interactions stimulate astrocyte migration and the retraction of neuronal prolongations, ...