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Antinociceptive and anti-exudative synergism between dexketoprofen and tramadol in a model of inflammatory pain in mice
(2012)
Preclinical studies have demonstrated antinociceptive synergism between dexketoprofen (DEX) and tramadol (TRM) in acute animal models of nociception. The aim of the present study was to investigate the type of interaction ...
Neostigmine interactions with non steroidal anti-inflammatory drugs
(2002)
1. The common mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of the enzyme cyclo-oxygenase (COX), however, this inhibition is not enough to completely account for the efficacy of ...
Anti-inflammatory, antinociceptive, and antipyretic effects of methanol extract of Cariniana rubra stem bark in animal models
(ACAD BRASILEIRA DE CIENCIAS, 2012)
Machaerium hirtum (Vell.) stellfeld alleviates acute pain and inflammation: Potential mechanisms of action
(2020-04-01)
Machaerium hirtum (Vell.) Stellfeld (Fabaceae) known in Brazil as “jacaranda de espinho” or “espinheira santa nativa” is a medicinal plant commonly used in folk medicine to treat ulcers, cough and diarrhea. This study aimed ...
Antinociceptive profile of 2,3,6-trisubstituted piperidine alkaloids: 3-O-acetyl-spectaline and semi-synthetic derivatives of (-)-spectaline
(Pharmaceutical Soc Japan, 2008-04-01)
In early studies, we have reported the antinociceptive profile of (-)-spectaline, a piperidine alkaloid from Cassia spectabilis. The present study describes the synthesis, the antinociceptive and anti-inflammatory activities ...
Antinociceptive profile of 2,3,6-trisubstituted piperidine alkaloids: 3-O-acetyl-spectaline and semi-synthetic derivatives of (-)-spectaline
(Pharmaceutical Soc Japan, 2008-04-01)
In early studies, we have reported the antinociceptive profile of (-)-spectaline, a piperidine alkaloid from Cassia spectabilis. The present study describes the synthesis, the antinociceptive and anti-inflammatory activities ...
Crotoxin: Novel activities for a classic beta-neurotoxin
(Pergamon-Elsevier B.V. Ltd, 2010-06-01)
Crotoxin, the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, was the first snake venom protein to be purified and crystallized. Crotoxin is a heterodimeric beta-neurotoxin that consists of ...
Crotoxin: Novel activities for a classic beta-neurotoxin
(Pergamon-Elsevier B.V. Ltd, 2010-06-01)
Crotoxin, the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, was the first snake venom protein to be purified and crystallized. Crotoxin is a heterodimeric beta-neurotoxin that consists of ...