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Endocrine Disorders in Sickle-Cell Disease
(2011)
Background: Sickle cell disease is a hemoglobinopathy of global importance due to its worldwide high prevalence. Endocrine and metabolic disorders may be associated with this disease, aggravating its clinical course. ...
Chronic stress and its effects on adrenal cortex apoptosis in pregnant rats
(Taylor & Francis, 2013-11)
The model of chronic intermittent stress by immobilization during pregnancy may produce alterations in the mechanisms that maintain adrenal gland homeostasis. In earlier investigations using this model, signifi cant ...
Comparative effect of FGF2, synthetic peptides 1-28 N-POMC and ACTH on proliferation in rat adrenal cell primary cultures
(SPRINGER, 2011)
There is evidence that pro-opiomelanocortin (POMC)-derived peptides other than adrenocorticotropic hormone (ACTH) have a role in adrenal cell proliferation. We compared the activity of synthetic rat N-terminal POMC fragment ...
Understanding cortisol action in acute inflammation. A view from the adrenal gland to the target cell Para entender la acción de cortisol en inflamación aguda: Una mirada desde la glándula suprarrenal hasta la célula blanco
(Sociedad Medica de Santiago, 2017)
© 2017 Rev Med Chile. All right reserved.Glucocorticoids (cortisol in humans) are essential for numerous biological functions. Among critically ill patients, therapy with cortisol has gained strength in recent years, but ...
Proliferating cell nuclear antigen immunoreaction in adrenal-tumors
(Casa Editrice Ambrosiana, 2015)
The proliferative effect of synthetic N-POMC(1-28) peptides in rat adrenal cortex: A possible role for cyclin E
(ELSEVIER IRELAND LTD, 2011)
Modified synthetic N-POMC(1-28) without disulfide bridges has been shown to act as an adrenal mitogen. Cyclins and their inhibitors are the major cell cycle controls, but in the adrenal cortex the effect of ACTH and N-POMC ...
Synthetic modified N-POMC(1-28) controls in vivo proliferation and blocks apoptosis in rat adrenal cortex
(SPRINGER, 2010)
The identity of the pro-opiomelanocortin (POMC)-derived mitogen in the adrenal cortex has been historically controversial. We have used well-established in vivo models, viz., hypophysectomized (Hyp) or dexamethasone ...
Crosstalk between nitric oxide synthases and cyclooxygenase 2 in the adrenal cortex of rats under lipopolysaccharide treatment
(Springer, 2013-11)
The effect of lipopolysaccharide on the modulation of steroid production by adrenal cells has been recently acknowledged. The purpose of this study was to determine the in vivo effects of LPS on adrenal cyclooxygenase ...