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Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension
(ELSEVIER SCIENCE INC, 2011)
Dietary nitrite and nitrate are important sources of nitric oxide (NO). However, the use of nitrite as an antihypertensive drug may be limited by increased oxidative stress associated with hypertension. We evaluated the ...
Rat ventral prostate xanthine oxidaseg-mediated metabolism of acetaldehyde to acetyl radical
(Sage Publications Ltd, 2009-04)
Alcohol drinking is known to lead to deleterious effects on prostate epithelial cells from humans and experimental animals. The understanding of the mechanisms underlying these effects is relevant to intraprostatic ethanol ...
Apple peel polyphenol extract protects against indomethacin-induced damage in Caco-2 cells by preventing mitochondrial Complex i inhibition
(2011)
The aim of this work was to investigate the role of mitochondrial dysfunction in the development of oxidative stress and cytotoxicity induced by indomethacin and to evaluate the potential of an apple peel polyphenol extract ...
Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (rubiaceae) in vitro and molecular docking studies
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-01)
Xanthine oxidase (XO), an enzyme widely distributed among mammalian tissues, is associated with the oxidation of xanthine and hypoxanthine to form uric acid. Reactive oxygen species are also released during this process, ...
Proximate composition and biological activity of Chilean Prosopis species
(WILEY, 2000)
The proximate and amino acid compositions of the leaves and pods of Prosopis chilensis and P tamarugo and the leaves of P alba have been assessed. The biological activity of the leaves and pods of the first two species as ...
Hypotensive effect and enzyme inhibition activity of mapuche medicinal plant extracts
(John Wiley & Sons Ltd., 2008)
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: Analysis of its potential role in heavy alcohol drinking tumor-promoting effects
(Wiley-liss, Inc, 2001-02)
The ability of the ventral prostate cytosolic fractions to biotransform ethanol to acetaldehyde and 1‐hydroxyethyl (1HEt) radicals was tested. Acetaldehyde formation was determined by GC‐FID analysis in the head space of ...