Buscar
Mostrando ítems 21-30 de 8596
Síntesis y caracterización de compósitos a base de resina de poliéster insaturado con micropartículas de cobre y cobre@plata (Cu@Ag) para ser aplicados potencialmente en la industria plástica como aditivo antibacterial
(Universidad Nacional Mayor de San MarcosPE, 2021)
La presente tesis tiene como objetivos proporcionar a la resina de poliéster insaturado (UPR)
la propiedad antibacteriana por la incorporación de MPs Cu y MPs Cu@Ag previamente
sintetizadas, así como modificar sus ...
Endoplasmic Reticulum Stress and the Hallmarks of Cancer
(Cell Press, 2016)
© 2016 Elsevier Inc. Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism ...
Gene Therapy Strategies to Restore ER Proteostasis in Disease
(Cell Press, 2018)
© 2018 The American Society of Gene and Cell Therapy Proteostasis alterations are proposed as a transversal hallmark of several pathological conditions, including metabolic disorders, mechanical injury, cardiac malfunction, ...
Function in the development of neurodegenerative diseases
(Frontiers Media S.A., 2018)
Copyright © 2018 García-González, Cabral-Miranda, Hetz and Osorio. Emerging evidence suggests that the immune and nervous systems are in close interaction in health and disease conditions. Protein aggregation and proteostasis ...
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
(2008)
The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of ...
Modulation of the Akt pathway reveals a novel link with PERK/eIF2alpha, which is relevant during hypoxia
(Public Library Science, 2013-07-29)
The unfolded protein response (UPR) and the Akt signaling pathway share several regulatory functions and have the capacity to determine cell outcome under specific conditions. However, both pathways have largely been studied ...
HIV infection and antiretroviral therapy lead to unfolded protein response activation
(BioMed Central, 2015)
ER chaperones in neurodegenerative disease: Folding and beyond
(Elsevier, 2016)
Proteins along the secretory pathway are co-translationally translocated into the lumen of the endoplasmic reticulum (ER) as unfolded polypeptide chains. Afterwards, they are usually modified with N-linked glycans, correctly ...
Mecanismo de activación de la respuesta a proteínas mal plegadas (UPR) en neuronas en un modelo de Glioblastoma
(Universidad Andrés Bello, 2023)
El glioblastoma multiforme (GB) es un tipo de tumor cerebral altamente agresivo con un
pronóstico desfavorable, una baja respuesta al tratamiento convencional y una alta tasa de
mortalidad. Se ha evidenciado que este ...