Buscar
Mostrando ítems 21-30 de 93
Interferon-a2b and transforming growth factor-b1 treatments on HCC cell lines: are Wnt/b-catenin pathway and Smads signaling connected in hepatocellular carcinoma?
(Elsevier Inc, 2011-12)
Wnt/b-catenin pathway is often dysregulated in hepatocellular carcinoma (HCC). Activated b-catenin accumulates in the cytosol and nucleus and forms a nuclear complex with TCF/LEF factors like TCF4. Interferon-a (IFN-a) has ...
Metabotropic glutamate receptor (mGlu3R) splicing variants in aging and Alzheimer´s disease
(Wiley, 2019)
Subtype 3 metabotropic glutamate receptors (mGlu3R) promote several neuroprotective effects, especially in glial cells. We have previously demonstrated that mGlu3R activation in astrocytes promotes the non-amyloidogenic ...
Approximate dual representation for Yang-Mills SU(2) gauge theory
(Springer, 2018-08-17)
An approximate dual representation for nonAbelian lattice gauge theories in terms of a new set of dynamical variables, the plaquette occupation numbers (PONs) that are natural numbers, is discussed. They are the expansion ...
Structure of the regulatory subunit of CK2 in the presence of a p21(WAF1) peptide demonstrates flexibility of the acidic loop
(BLACKWELL MUNKSGAARD, 2004-10)
A truncated form of the regulatory subunit of the protein kinase CK2beta ( residues 1 - 178) has been crystallized in the presence of a fragment of the cyclin-dependent kinase inhibitor p21(WAF1) ( residues 46 - 65) and ...
Heart and liver T2* assessment for iron overload using different software programs
(SpringerNew YorkEUA, 2011)
Ciclo de vida domiciliar, ciclo de vida do lote e dinâmica da cobertura da terra em Machadinho, Amazônia Brasileira
(Universidade Federal de Minas GeraisUFMG, 2016-02-05)
Deforestation is one of the main problems associated with environmental degradation of the Amazon borders. Much of the high rates of deforestation in the Amazon are the result of human occupation that generates clearing ...
A Novel Splice Variant of Human TGF-β Type II Receptor Encodes a Soluble Protein and Its Fc-Tagged Version Prevents Liver Fibrosis in vivo
(Frontiers Media, 2021-09-10)
We describe, for the first time, a new splice variant of the human TGF-β type II receptor (TβRII). The new transcript lacks 149 nucleotides, resulting in a frameshift and the emergence of an early stop codon, rendering a ...
Biophysical characterization of the recombinant importin-α from neurospora crassa
(2013-02-01)
Neurospora crassa has been widely used as a model organism and contributed to the development of biochemistry and molecular biology by allowing the identification of many metabolic pathways and mechanisms responsible for ...