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Two-dimensional transport analysis of transdermal drug absorption with a non-perfect sink boundary condition at the skin-capillary interface
(ELSEVIER SCIENCE INC, 2013-07-01)
A transient percutaneous drug absorption model was solved in two dimensions. Clearance of the topically-applied pharmaceutical occured at the skin-capillary boundary. Timolol penetration profiles in the dermal tissue were ...
Insights into Protein-Ionic Liquid Interactions Aiming at Macromolecule Delivery Systems
(Soc Brasileira Quimica, 2018-10-01)
Over the last few years, researchers have started to explore a particular class of compounds defined as ionic liquids (ILs) in attempts to use their unique characteristics. Since ILs have a very low vapor pressure, these ...
Design and analyses of a transdermal drug delivery device (TD3 )
(MDPIBasel, Switzerland, 2019)
In this paper, we introduce a novel type of transdermal drug delivery device (TD3 ) with a micro-electro-mechanical system (MEMS) design using computer-aided design (CAD) techniques as well as computational fluid dynamics ...
Recent advances in micro-electro-mechanical devices for controlled drug release applications
(Frontiers Media S.A., 2020-06)
In recent years, controlled release of drugs has posed numerous challenges with the aim of optimizing parameters such as the release of the suitable quantity of drugs in the right site at the right time with the least ...
Comparative study of transdermal drug delivery systems of resveratrol: High efficiency of deformable liposomes
(Elsevier Science, 2018-09)
Trans-resveratrol (3, 5, 4′ trihydroxystilbene, RSV) is a natural compound that shows antioxidant, cardioprotective, anti-inflammatory and anticancer properties. The transdermal, painless application of RSV is an attractive ...
Bioadhesive Films Containing Benzocaine: Correlation Between In Vitro Permeation and In Vivo Local Anesthetic Effect
(Springer/plenum PublishersNew YorkEUA, 2010)
Engineering Thermoresponsive Polyether-Based Nanogels for Temperature Dependent Skin Penetration
(Royal Society of Chemistry, 2015-06)
Highly biocompatible thermoresponsive nanogels (tNGs) based on oligo ethylene glycol (OEG) as thermoresponsive unit and dendritic polyglycerol (dPG) as cross-linker, were precisely engineered in terms of size and volume ...
Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes
(Springer New York LLC, 2017)
© 2017, American Association of Pharmaceutical Scientists. Biologic products are large molecules such as proteins, peptides, nucleic acids, etc., which have already produced many new drugs for clinical use in the last ...