Buscar
Mostrando ítems 21-30 de 35538
In vitro assessment of the cytotoxic, apoptotic, and mutagenic potentials of Isatin
(2013-03-01)
Isatin (1H-indole-2,3-dione) is a chemical found in various medicinal plant species and responsible for a broad spectrum of pharmacological and biological properties that may be beneficial to human health, as an anticonvulsant, ...
Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
(BioMed Central, 2016)
Abstract
Background
Lichen planus (LP) is a chronic mucocutaneous inflammatory disease. Evaluating the balance between regulatory T cells and effector T cells could be ...
Cell death and the immune response of the sipunculid worm Themiste petricola
(University of Modena and Reggio Emilia, 2010-09)
We have recently studied the role of cell death in the immune system of the sipunculan worm Themiste petricola. Typical biochemical and morphological changes of apoptosis were induced in celomocytes of these marine worms ...
Th17 and Treg cells, two new lymphocyte subpopulations with a key role in the immune response against infection
(2008)
In addition to the T helper 1 (Th1) and Th2 lymphocyte subsets, two new subpopulations Th17 and regulatory T
(Treg) cells have recently been described. Th17 cells, which produce high levels of interleukin (IL)-17, ...
Therapeutic potential of hyporesponsive CD4+ T cells in autoimmunity
(Frontiers Media S.A., 2015)
© 2015 Maggi, Schafer, Ubilla-Olguín, Catalán, Schinnerling and Aguillón. The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs ...
Tissue-resident memory CD8(+) T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells
(Facultad de Medicina y Ciencia, 2019)
Tissue-resident memory CD8(+) T (Trm) cells mediate potent local innate and adaptive immune responses and play a central role against solid tumors. However, whether Trm cells cross-talk with dendritic cells (DCs) to support ...
Blocking drug-induced autophagy with chloroquine in HCT-116 colon cancer cells enhances DC maturation and T cell responses induced by tumor cell lysate
(2020-07-01)
Autophagy is an important mechanism for tumor escape, allowing tumor cells to recover from the damage induced by chemotherapy, radiation therapy, and immunotherapy and contributing to the development of resistance. The ...
Early T follicular helper cell responses and germinal center reactions are associated with viremia control in immunized rhesus macaques
(American Society for Microbiology, 2019)
T follicular helper (T FH ) cells are fundamental in germinal center (GC) maturation and selection of antigen-specific B cells within secondary lymphoid organs. GC-resident T FH cells have been fully characterized in human ...
T-cell deficiency and hyperinflammatory monocyte responses associate with Mycobacterium avium complex lung disease
(Frontiers Media, 2022)
Immunological mechanisms of susceptibility to nontuberculous mycobacterial (NTM) disease are poorly understood. To understand NTM pathogenesis, we evaluated innate and antigen-specific adaptive immune responses to Mycobacterium ...