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Synergistic effect of mycophenolate mofetil and angiotensin-converting enzyme inhibitor in patients with chronic allograft nephropathy
(Associação Brasileira de Divulgação Científica, 2009-05-01)
Experimental data and few clinical non-randomized studies have shown that inhibition of the renin-angiotensin system by angiotensin-converting enzyme (ACE) associated or not with the use of mycophenolate mofetil (MMF) could ...
Pharmacogenetic effects of angiotensin-converting enzyme inhibitors over age-related urea and creatinine variations in patients with dementia due to Alzheimer disease
(Corporacion Editora Medica Valle, 2016)
Background: Renal function declines according to age and vascular risk factors, whereas few data are available regarding genetically-mediated effects of anti-hypertensives over renal function. Objective: To estimate urea ...
Leptin regulates ACE activity in mice
(Springer, 2010-09-01)
Leptin is a hormone related to metabolism. It also influences blood pressure, but the mechanisms triggered in this process are not yet elucidated. Angiotensin-I converting enzyme (ACE) regulates cardiovascular functions ...
Peptidase activities in rats treated chronically with N-omega-nitro-L-arginine methyl ester (L-NAME)
(Pergamon-elsevier Science LtdOxfordInglaterra, 2004)
An Update On The Pharmacogenetics Of Treating Hypertension
(NATURE PUBLISHING GROUPLONDON, 2015)
Tachycardia during the onset of one-kidney, one-clip renal hypertension: role of the renin-angiotensin system and AV3V tissue
(1988-04-19)
We have previously demonstrated a transitory tachycardia during the early phase of one kidney, one clip (1K1C) hypertension in the rat, when the basal heart rate (HR) is measured daily under resting conditions. In the ...
Low-dose Enalapril Reduces Angiotensin II and Attenuates Diabetic-induced Cardiac and Autonomic Dysfunctions
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
Activation of renin-angiotensin system has been linked to cardiovascular and autonomic dysfunctions in diabetes. Experiments were performed to investigate the effects of angiotensin-converting enzyme inhibitor (ACEI), ...
Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Informa Healthcare, 2017-08)
Introduction: Currently, available therapies for Parkinson’s disease (PD) are symptomatic. Therefore, the search for neuroprotective drugs remains a top priority. Areas covered: In this review, the potential symptomatic ...
Effect of angiotensin converting enzyme inhibitor enalapril on body weight and composition in young rats
(ELSEVIER SCIENCE BV, 2008)
Obesity is considered a worldwide public health problem showing an increased prevalence in developing countries, with urgent need for new and more efficient drugs and therapies. Enalapril, an angiotensin-I converting enzyme ...