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Rab35 functions in axon elongation are regulated by p53-related protein kinase (prpk) in a mechanism that involves rab35 protein degradation and the microtubule-associated protein 1b
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat primary neurons in an ...
Rab35 functions in axon elongation are regulated by PRPK in a mechanism that involves Rab35 protein degradation and MAP1B
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal
immortalized cells, Rab35 promotes neurite differentiation. Here we describe that
Rab35 favors axon elongation in rat primary neurons in an ...
Rab35 functions in axon elongation are regulated by p53-related protein kinase in a mechanis that involves Rab35 protein degradation and the microtubule-associated protein 1B
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat primary neurons in an ...
Rab1b overexpression modifies Golgi size and gene expression in HeLa cells and modulates the thyrotrophin response in thyroid cells in culture
(American Society for Cell Biology, 2013-01)
Rab1b belongs to the Rab-GTPase family that regulates membrane trafficking and signal transduction systems able to control diverse cellular activities, including gene expression. Rab1b is essential for endoplasmic ...
The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions.
(Company of Biologists, 2015-08)
Given their obligate intracellular lifestyle, Chlamydia trachomatis ensure their access to multiple host sources of essential lipids by interfering vesicular transport. These bacteria hijack Rab6-, Rab11- and Rab14-controlled ...
Tuba activates cdc42 during neuronal polarization downstream of the small gtpase rab8a
(Society for Neuroscience, 2021-02)
The acquisition of neuronal polarity is a complex molecular process that depends on changes in cytoskeletal dynamics and directed membrane traffic, regulated by the Rho and Rab families of small GTPases, respectively. ...
Grab recruitment by Rab27A-Rabphilin3a triggers Rab3A activation in human sperm exocytosis
(Elsevier Science, 2019-04)
Sperm must undergo the regulated exocytosis of its dense core granule (the acrosome reaction, AR) to fertilize the egg. We have previously described that Rabs3 and 27 are organized in a RabGEF cascade within the signaling ...
Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction
(CIENCIAS, 2011)
OBJECTIVE: Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
Nuclear accumulation of beta-catenin is associated with endosomal sequestration of the destruction complex and increased activation of Rab5 in oral dysplasia
(Wiley, 2020)
Potentially malignant lesions, commonly referred to as dysplasia, are associated with malignant transformation by mechanisms that remain unclear. We recently reported that increased Wnt secretion promotes the nuclear ...
Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction
(WILEY-BLACKWELL, 2011-10)
Objective. Oral and ocular dryness are frequent and serious symptoms of Sjogren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...