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High Proteasome Activity in Plasma of Patients with Hematologic Malignancy (Case of 145 Moroccan patients)
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Thermoplasma acidophilum TAA43 is an archaeal member of the eukaryotic meiotic branch of AAA ATPases
(Walter de Gruyter GmbH, 2019)
Age-dependent protein modifications and declining proteasome activity in the human lens
(ELSEVIER SCIENCE INC, 2004)
The proteasome is known to be the main enzymatic complex responsible for the intracellular degradation of altered proteins, and the age-related accumulation of modified lens proteins is associated to the formation of ...
Proteasome Inhibition Represses Unfolded Protein Response and Nox4, Sensitizing Vascular Cells to Endoplasmic Reticulum Stress-Induced Death
(PUBLIC LIBRARY SCIENCE, 2011)
Background: Endoplasmic reticulum (ER) stress has pathophysiological relevance in vascular diseases and merges with proteasome function. Proteasome inhibition induces cell stress and may have therapeutic implications. ...
Reduced levels of proteasome products in a mouse striatal cell model of huntington's disease
(2015-12-01)
Huntington's disease is the result of a long polyglutamine tract in the gene encoding huntingtin protein, which in turn causes a large number of cellular changes and ultimately results in neurodegeneration of striatal ...
20S proteasome and accumulation of oxidized and ubiquitinated proteins in maize leaves subjected to cadmium stress
(Pergamon-Elsevier Science Ltd, 2007-04)
In order to examine the possible involvement of the 20S proteasome in degradation of oxidized proteins, the effect of different cadmium concentrations on its activities, protein abundance and oxidation level were studied ...
Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS)
(Frontiers, 2019)
Type I interferonopathies cover a phenotypically heterogeneous group of rare genetic diseases including the recently described proteasome-associated autoinflammatory syndromes (PRAAS). By definition, PRAAS are caused by ...