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Two short peptides including segments of subunit A of Escherichia coli DNA gyrase as potential probes to evaluate the antibacterial activity of quinolones
(2001-03-10)
Quinolones constitute a family of compounds with a potent antibiotic activity. The enzyme DNA gyrase, responsible for the replication and transcription processes in DNA of bacteria, is involved in the mechanism of action ...
Two short peptides including segments of subunit A of Escherichia coli DNA gyrase as potential probes to evaluate the antibacterial activity of quinolones
(2001-03-10)
Quinolones constitute a family of compounds with a potent antibiotic activity. The enzyme DNA gyrase, responsible for the replication and transcription processes in DNA of bacteria, is involved in the mechanism of action ...
A 4.2 kDa synthetic peptide as a potential probe to evaluate the antibacterial activity of coumarin drugs
(Wiley-Blackwell, 2004-09-01)
The coumarin antibiotics are potent inhibitors of DNA replication whose target is the enzyme DNA gyrase, an ATP-dependent bacterial type II topoisomerase. The coumarin drugs inhibit gyrase action by competitive binding to ...
A 4.2 kDa synthetic peptide as a potential probe to evaluate the antibacterial activity of coumarin drugs
(Wiley-Blackwell, 2004-09-01)
The coumarin antibiotics are potent inhibitors of DNA replication whose target is the enzyme DNA gyrase, an ATP-dependent bacterial type II topoisomerase. The coumarin drugs inhibit gyrase action by competitive binding to ...
Targeting tumors using peptides
(Multidisciplinary Digital Publishing Institute, 2020-02)
To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure ...
Triple GLP-1/GIP/glucagon receptor agonists, a potential novel treatment strategy in Alzheimer’s disease
(Taylor and Francis Ltd, 2019)
Peptide Prodrugs for the Treatment of CNS Disorders: A Perspective for New Drugs
(Bentham Science Publ Ltd, 2014)