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In vitro effects of environmental isolates of Acanthamoeba T4 and T5 over human erythrocytes and platelets
(2020-01-21)
Free-living amoebae of the genus Acanthamoeba have been associated with keratitis and encephalitis. Some factors related to their pathogenic potential have been described, including the release of hydrolytic enzymes, and ...
Enzimas que hidrolisam nucleotídeos de adenina em plaquetas, agregação plaquetária e polimorfismo do gene α2 da integrina α2β1 em pacientes com a doença de von Willebrand
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2009-04-08)
Von Willebrand disease (vWD) is one of the most common inherited bleeding diseases, caused by a qualitative or quantitative deficiency of the von Willebrand factor (vWF). vWF is a multimeric glycoprotein synthesized by ...
Crystallization and preliminary diffraction data of a platelet-aggregation inhibitor from the venom of Agkistrodon piscivorus piscivorus (North American water moccasin)
(Munksgaard Int Publ Ltd, 1999-08-01)
Applaggin (Agkistrodon piscivorus piscivorus platelet-aggregation inhibitor) is a potent inhibitor of blood platelet aggregation derived from the venom of the North American water moccasin, the protein consists of 71 amino ...
The role of sex steroids on cellular events involved in vascular disease
(Pergamon-Elsevier Science Ltd, 2012-11)
In this work we checked the hypothesis whether estrone, progesterone, and testosterone are able to modulate the interactions between platelets, monocytes, and endothelial cells either under basal or inflammatory conditions. ...
Marked bleeding diathesis in patients with platelet dysfunction due to a novel mutation in RASGRP2, encoding CalDAG-GEFI (p.Gly305Asp)
(Taylor & Francis Ltd, 2018-01)
Congenital platelet function disorders are often the result of defects in critical signal transduction pathways required for platelet adhesion and clot formation. Mutations affecting RASGRP2, the gene encoding the Rap ...