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Excess iodide downregulates Na+/I− symporter gene transcription through activation of PI3K/Akt pathway
(Elsevier Ireland, 2016-05)
Transcriptional mechanisms associated with iodide-induced downregulation of NIS expression remain uncertain. Here, we further analyzed the transcriptional regulation of NIS gene expression by excess iodide using PCCl3 ...
Papel de la vía fosfatidilinositol 3 kinasa (PI3K/Akt) en humanos
(Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)
The signaling pathway of phosphatidylinositol 3-kinase (PI3K) is critical in many aspects of growth and cell survival. The path of PI3K is stimulated physiologically as a result of many growth factors and regulatory factors. ...
Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells
(Molecular Cancer 2013, 12:44, 2013)
Adiponectin and Serine/Threonine Kinase Akt Modulation by Triiodothyronine and/or LY294002 in 3T3-L1 Adipocytes
(2019-02-01)
Adipose tissue (AT), an endocrine organ that modulates several physiological functions by synthesizing and releasing adipokines such as adiponectin, is a metabolic target of triiodothyronine (T3). T3 and adiponectin play ...
Genetic-molecular study of the EGFR/PI3K/AKT pathway in high and low grade gliomas
Gliomas account for 70% of all central nervous system (CNS) tumors and are classified according to the WHO in low (I and II) or high (III and IV or glioblastoma multiforme, GBM) grade malignancies. The survival of patients ...
Genetic-molecular study of the egfr/ pi3k/akt pathway in high and low grade gliomas
Gliomas account for 70% of all central nervous system (CNS) tumors and are classified according to the WHO in low (I and II) or high (III and IV or glioblastoma multiforme, GBM) grade malignancies. The survival of patients ...
PI3K/AKT signaling drives titanium-induced angiogenic stimulus
(2021-01-01)
Although osseointegration and clinical success of titanium (Ti)-implanted materials depend on neovascularization in the reactional peri-implant tissue, very little has been achieved considering the Ti-molecules release on ...