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PAMAM dendrimers functionalized with ruthenium nitrosyl as nitric oxide carriers
(Elsevier BVAmsterdam, 2014-01)
The functionalization of three generations of polyamidoamine (PAMAM G0, G2 and G3) dendrimers with the NO-donor trans-[Ru(NO)(NH3)4(ina)](BF4)3 (ina = isonicotinic acid) is reported. PAMAMs were modified through a peptide-type ...
The hypotensive effect of the ruthenium complex [Ru(terpy)(bdq)NO](3+) is higher in male than in female spontaneously hypertensive rats (SHR)
(Springer, 2014-11-01)
We have previously demonstrated that the hypotensive effect of the ruthenium complex [Ru(terpy)(bdq)NO](3+) (TERPY) is slow, long lasting, and does not lead to reflex tachycardia. TERPY's hypotensive effect is increased ...
SNP as an Effective Donor of Nitric Oxide for in vitro Plant Cell and Tissue Culture
(OMICS Publishing Group, 2014)
Experimental Chemotherapy in Paracoccidioidomycosis Using Ruthenium NO Donor
(SPRINGER, 2011)
Paracoccidioidomycosis (PCM) is a granulomatous disease caused by a dimorphic fungus, Paracoccidioides brasiliensis (Pb). To determine the influence of nitric oxide (NO) on this disease, we tested cis-[Ru(bpy)2(NO)SO3](PF6), ...
Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity
(Elsevier MassonIssy les Moulineaux, 2014-07)
Hybrid bioisoster derivatives from N-acylhydrazones and furoxan groups were designed with the objective of obtaining at least a dual mechanism of action: cruzain inhibition and nitric oxide (NO) releasing activity. Fifteen ...
NO donors-relaxation is impaired in aorta from hypertensive rats due to a reduced involvement of K+ channels and sarcoplasmic reticulum Ca2+-ATPase
(2011)
Aims: To examine the vasodilatation induce by the NO donors, [Ru(terpy)(bdq)NO]3+ (TERPY) and sodium nitroprusside (SNP), and to compare their effects in aortic rings from hypertensive 2K-1C and normotensive 2K
rats. Main ...
Polynitrosated polyesters: Preparation, characterization, and potential use for topical nitric oxide release
(Amer Chemical SocWashingtonEUA, 2005)