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Nelfinavir-Resistant, Amprenavir-Hypersusceptible Strains of Human Immunodeficiency Virus Type 1 Carrying an N88S Mutation in Protease Have Reduced Infectivity, Reduced Replication Capacity, and Reduced Fitness and Process the Gag Polyprotein Precursor Aberrantly
(American Society for Microbiology, 2002-09)
The evolution of human immunodeficiency virus type 1 (HIV-1) strains with reduced susceptibility to protease inhibitors (PIs) is a major cause of PI treatment failure. A subset of subjects failing a therapy regimen containing ...
Consenso em criptococose - 2008
(2008-09-01)
Consenso em criptococose - 2008
(2008-09-01)
Efeito do uso diário da associação estavudina / mesilato de nelfinavir sobre toda a prenhez da rata albina: ensaio biológico
(Universidade Federal de São Paulo (UNIFESP), 2010)
Objetivo: Investigar o efeito do uso diario da associacao estavudina/mesilato de nelfinavir sobre toda a prenhez da rata albina. Materiais e metodos: 40 ratas albinas gravidas EPM-Wistar (Rattus norvegicus albinus) foram ...
Effectiveness of commercial inhibitors against subtype F HIV-1 protease
(TAYLOR & FRANCIS LTD, 2009)
Subtype F wild type HIV protease has been kinetically characterized using six commercial inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir) commonly used for HIV/AIDS treatment, as well as ...
Antiviral Resistance and Correlates of Virologic Failure in the first Cohort of HIV-Infected Children Gaining Access to Structured Antiretroviral Therapy in Lima, Peru: A Cross-Sectional Analysis
(BioMed Central, 2013)
Background: The impact of extended use of ART in developing countries has been enormous. A thorough understanding of all factors contributing to the success of antiretroviral therapy is required. The current study aims to ...