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Methionine- and choline-deficient diet induces hepatic changes characteristic of non-alcoholic steatohepatitis
(Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia - IBEPEGE, 2016)
Non-alcoholic fatty liver disease and insulin resistance: importance of risk factors and histological spectrum
(2005)
Background: Non-alcoholic fatty liver disease (NAFLD) has been associated with several metabolic conditions (MC) and secondary causes, but the relationship between insulin resistance (IR) and the underlying aetiology of ...
Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease
(Elsevier B.V., 2018)
© 2018 The global epidemic of obesity has been accompanied by a rising burden of non-alcoholic fatty liver disease (NAFLD), with manifestations ranging from simple steatosis to non-alcoholic steatohepatitis, potentially ...
Relationship between in vivo chlorzoxazone hydroxylation, hepatic cytochrome P450 2E1 content and liver injury in obese non-alcoholic fatty liver disease patients
(2006)
The aim of the present study was to test the hypothesis that induction of cytochrome P450 2E1 (CYP2E1) in the liver of patients with non-alcoholic fatty liver disease (NAFLD) is correlated both with the in vivo activity ...
Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome
(BioMed Central, 2017)
Abstract
Background
Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin–angiotensin ...
Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease
(Associação Brasileira de Divulgação Científica, 2005-05-01)
Hepatic fibrosis in patients with non-alcoholic fatty liver disease is associated with progression of the disease. In the present study, we analyzed the discriminative ability of serum laminin, type IV collagen and hyaluronan ...
Assessment of hepatic fatty acids during non-alcoholic steatohepatitis progression using magnetic resonance spectroscopy
(2021)
Abstract: Introduction and objectives: Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver abnormalities including steatosis, steatohepatitis, fibrosis, and cirrhosis. Liver biopsy remains the gold ...
Trypanosoma cruzi Infection Is a Potent Risk Factor for Non-alcoholic Steatohepatitis Enhancing Local and Systemic Inflammation Associated with Strong Oxidative Stress and Metabolic Disorders
(Public Library of Science, 2015-02)
The immune mechanisms underlying experimental non-alcoholic steatohepatitis (NASH), and more interestingly, the effect of T. cruzi chronic infection on the pathogenesis of this metabolic disorder are not completely understood. ...
Methionine- and choline-deficient diet induces hepatic changes characteristic of non-alcoholic steatohepatitis
(Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia - IBEPEGE, 2011)
Sorafenib reduces steatosis-induced fibrogenesis in a human 3D co-culture model of non-alcoholic fatty liver disease
(2020-01-01)
Non-alcoholic fatty liver disease (NAFLD) affects around 25% of the worldwide population. Non-alcoholic steatohepatitis (NASH), the more progressive variant of NAFLD, is characterized by steatosis, cellular ballooning, ...