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Methylpiperidinium Iodides as novel antagonists for alpha 7 nicotinic acetylcholine receptors
(Frontiers Media, 2018)
The alpha 7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important drug target. We have designed and ...
Methylpiperidinium iodides as novel antagonists for α7 nicotinic acetylcholine receptors
(Frontiers Media S.A., 2018)
© 2018 López, García-Colunga, Pérez and Fierro. The α7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important ...
Erythrina mulungu Alkaloids Are Potent Inhibitors of Neuronal Nicotinic Receptor Currents in Mammalian Cells
(Public Library Science, 2013-12-13)
Crude extracts and three isolated alkaloids from Erythrina mulungu plants have shown anxiolytic effects in different animal models. We investigated whether these alkaloids could affect nicotinic acetylcholine receptors and ...
Melatonin and the time window for the expression of the alpha 8 nicotinic acetylcholine receptor in the membrane of chick retinal cells in culture
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
We have previously shown that melatonin influences the development of alpha 8 nicotinic acetylcholine receptor (nAChR) by measurement of the acetylcholine-induced increase in the extracellular acidification rate (ECAR) in ...
Effects of acetylcholine and cholinergic antagonists on the activity of nucleus of the solitary tract neurons
(Elsevier B.V., 2017-03-15)
Previously we have demonstrated that microinjection of acetylcholine (ACh) into the intermediate nucleus of the solitary tract (iNTS) induced sympatho-inhibition combined with a decrease in the phrenic nerve activity (PNA), ...
The Hair Cell α9α10 Nicotinic Acetylcholine Receptor: Odd Cousin in an Old Family
(Frontiers Media, 2021-11-15)
Nicotinic acetylcholine receptors (nAChRs) are a subfamily of pentameric ligand-gated ion channels with members identified in most eumetazoan clades. In vertebrates, they are divided into three subgroups, according to their ...