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Investigation of the Effects of a1-Adrenoceptor Antagonism and L-Type Calcium Channel Blockade on Ejaculation and Vas Deferens and Seminal Vesicle Contractility In Vitro
(Wiley-Blackwell, 2012-01-01)
Introduction. Premature ejaculation is one of the most common male sexual dysfunctions. Current pharmacological treatments involve reduction in penile sensitivity by local anesthetics or increase of ejaculatory threshold ...
Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker
(NATL ACAD SCIENCES, 2001-08-14)
Upon depolarization positive charges contained in the transmembrane segment S4 of voltage-dependent channels are displaced from the cytoplasmic to the external milieu, This charge movement leads to channel opening. In ...
Histochemical differences in the responses of predominantly fast-twitch glycolytic muscle and slow-twitch oxidative muscle to veratrine
(Pergamon-elsevier Science LtdOxfordInglaterra, 2002)
The Critical Role of Intrinsic Membrane Oscillations
(Karger, 2019-04)
Intrinsic, rhythmic subthreshold oscillations have been described in neurons of regions throughout the brain and have been found to influence the timing of action potentials induced by synaptic inputs. Some oscillations ...
Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons
(Wiley Blackwell Publishing, Inc, 2014-06)
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in food intake and energy expenditure regulation. MC4R activation modifies neuronal activity but the molecular mechanisms by which this regulation ...
Calcium channel subtypes differentially regulate fusion pore stability and expansion
(2007)
Various studies have focused in the relative contribution of different voltage-activated Ca2+ channels (VACC) to total transmitter release. However, how Ca2+ entry through a given VACC subtype defines the pattern of ...
L-Type calcium channels mediate water intake induced by angiotensin injection into median preoptic nucleus
(Elsevier B.V., 2006-04-01)
Calcium ions are widely accepted as critically important in responses of neurons to a stimulus. We have show previously the central involvement of angiotensin II (ANGII) in water intake. This study determined whether ...
L-Type calcium channels mediate water intake induced by angiotensin injection into median preoptic nucleus
(Elsevier B.V., 2006-04-01)
Calcium ions are widely accepted as critically important in responses of neurons to a stimulus. We have show previously the central involvement of angiotensin II (ANGII) in water intake. This study determined whether ...