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Energy Metabolism in Cardiac Remodeling and Heart Failure
(2013-05-01)
Fatty acids are the main substrates used by mitochondria to provide myocardial energy under normal conditions. During heart remodeling, however, the fuel preference switches to glucose. In the earlier stages of cardiac ...
Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury
(Lippincott Williams and Wilkins, 2014)
Mitochondria are key organelles for ATP production in cardiomyocytes, which is regulated by processes of fission and fusion. We hypothesized that the mitochondria fusion protein dynamin-related protein 1 (Drp1) inhibition, ...
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression
(AMER PHYSIOLOGICAL SOC, 2008)
Virtually every mammalian cell, including cardiomyocytes, possesses an intrinsic circadian clock. The role of this transcriptionally based molecular mechanism in cardiovascular biology is poorly understood. We hypothesized ...
Use of beta-blockers for the treatment of cardiac arrest due to ventricular fibrillation/pulseless ventricular tachycardia: A systematic review
(Elsevier B.V., 2012-06-01)
Introduction: Advanced Life Support guidelines recommend the use of epinephrine during Cardiopulmonary Resuscitation (CPR), as to increase coronary blood flow and perfusion pressure through its alpha-adrenergic peripheral ...
Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats
(Universidade Estadual Paulista, 2017)
Exercício físico aeróbio potencializa a terapia com células-tronco mesenquimais derivadas do tecido adiposo em ratos com infarto do miocárdio
(Universidade Federal de São Paulo (UNIFESP), 2016-11-11)
Aims: To analyze the effect of prior exercise training to myocardial infarction (MI) in the cardiac remodeling of rats undergoing therapy with mesenchymal stem cells from adipose tissue (ADSC). Methods: The study included ...
Qualidade de vida após infarto agudo do miocárdio: avaliação com os questionários Mac New QLMI e SF-36Quality of life after acute myocardial infarction: evaluation with the MacNew QLMI and SF-36 questionnaires
(Universidade Federal de UberlândiaBRPrograma de Pós-graduação em Ciências da SaúdeCiências da SaúdeUFU, 2016)