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Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells
(2019)
Background:
Epanorin (EP) is a secondary metabolite of the Acarospora lichenic species. EP has been found in lichenic extracts with antimicrobial activity, and UV-absorption properties have been described for closely ...
Targeted Mutagenesis in Pathogenic Leptospira Species: Disruption of the LigB Gene Does Not Affect Virulence in Animal Models of Leptospirosis
(AMER SOC MICROBIOLOGY, 2008)
The pathogenic mechanisms of Leptospira interrogans, the causal agent of leptospirosis, remain largely unknown. This is mainly due to the lack of tools for genetically manipulating pathogenic Leptospira species. Thus, ...
Domain folding and flexibility of Escherichia coli FtsZ determined by tryptophan site-directed mutagenesis
(COLD SPRING HARBOR LAB PRESS, 2007-08)
FtsZ has two domains, the amino GTPase domain with a Rossmann fold, and the carboxyl domain that
resembles the chorismate mutase fold. Bioinformatics analyses suggest that the interdomain interaction
is stronger than the ...
Generación, selección y caracterización bioquímica y cinética de cepas mutantes de Phaeodactylum tricornutum (Bohlin)
(Centro de Investigaciones Biológicas del Noroeste, S.C., 2003)
Estudio racional del mecanismo de unión y catalítico de alcohol veratrílico en Lignino peroxidasa H8 de Phanerochaete chrysosporium: una estrategia in-silico/experimental
(Universidad de Talca (Chile). Instituto de Química de Recursos Naturales., 2019)
Study of the Cys-His bridge electron transfer pathway in a copper-containing nitrite reductase by site-directed mutagenesis, spectroscopic, and computational methods
(Elsevier Science, 2018-03)
The Cys-His bridge as electron transfer conduit in the enzymatic catalysis of nitrite to nitric oxide by nitrite reductase from Sinorhizobium meliloti 2011 (SmNir) was evaluated by site-directed mutagenesis, steady state ...
DNA damage in chronic diseases and aging
(Elsevier B.V., 2015-06-01)
Tn5AraOut mutagenesis for the identification of Yersinia pestis genes involved in resistance towards cationic antimicrobial peptides
(Elsevier, 2011-05)
Bacterial pathogens display a variety of protection mechanisms against the inhibitory and lethal effects of host cationic antimicrobial peptides (CAMPs). To identify Yersinia pestis genes involved in CAMP resistance, ...