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Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans
(Sociedade Brasileira de Genética, 2010)
Several studies have shown that mutations and polymorphisms in clock genes are associated with abnormal circadian parameters in humans and also with more subtle non-pathological phenotypes like chronotypes. However, there ...
Intra- and interspecific divergence in the nuclear sequences of the clock gene period in species of the Drosophila buzzatii cluster
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
We have measured nucleotide variation in the CLOCK/CYCLE heterodimer inhibition domain (CCID) of the clock X-linked gene period in seven species belonging to the Drosophila buzzatii cluster, namely D. buzzatii, Drosophila ...
Molecular dates require geologic testing
(Wiley Blackwell Publishing, Inc, 2016-03)
Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
(National Academy of Sciences, 2016-04)
This study defines a molecular mechanism for how clock- and light-signaling pathways converge in Arabidopsis. The data reveal that TOC1, an essential core component of the central oscillator, binds to and represses PIF ...
Perinatal Programming of Circadian Clock-Stress Crosstalk
(Hindawi Publishing Corporation, 2018-02)
An intact communication between circadian clocks and the stress system is important for maintaining physiological homeostasis under resting conditions and in response to external stimuli. There is accumulating evidence for ...
Alternative splicing adds a new loop to the circadian clock
(Landes Bioscience, 2011-05)
Circadian clocks allow organisms to adjust multiple physiological and developmental processes in anticipation of daily and seasonal changes in the environment. At the molecular level these clocks consist of interlocked ...