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Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer’s Disease
(Humana Press Inc., 2018)
The role of mitochondrial impairment in alzheimer´s disease neurodegeneration: The Tau connection
(Bentham Science Publishers, 2020)
Accumulative evidence has shown that mitochondrial dysfunction plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). Mitochondrial impairment actively contributes to the synaptic and cognitive failure that ...
The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis
(Elsevier Ireland, 2015-06)
The steroidogenic acute regulatory (StAR) protein regulates the rate-limiting step in steroidogenesis, i.e. the delivery of cholesterol from the outer (OMM) to the inner (IMM) mitochondrial membrane. StAR is a 37-kDa protein ...
Diabetes impairs heart mitochondrial function without changes in resting cardiac performance
(Pergamon-Elsevier Science Ltd, 2016-12)
Diabetes is a chronic disease associated to a cardiac contractile dysfunction that is not attributable to underlying coronaryartery disease or hypertension, and could be consequence of a progressive deterioration of ...
Development or disease: duality of the mitochondrial permeability transition pore
(Academic Press Inc., 2017)
Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons
(Humana Press, 2018-12)
Mitochondria are widely recognized as fundamental organelles for cellular physiology and constitute the main energy source for different cellular processes. The location, morphology, and interactions of mitochondria with ...
Evolution of the Metazoan Mitochondrial Replicase
(Oxford Univ Press, 2015-04-01)
The large number of complete mitochondrial DNA (mtDNA) sequences available for metazoan species makes it a good system for studying genome diversity, although little is known about the mechanisms that promote and/or are ...
Nitric Oxide in Skeletal Muscle: Role on Mitochondrial Biogenesis and Function
(Mdpi Ag, 2012-12-01)
Nitric oxide (NO) has been implicated in several cellular processes as a signaling molecule and also as a source of reactive nitrogen species (RNS). NO is produced by three isoenzymes called nitric oxide synthases (NOS), ...
Mitochondrial Alterations in Nonalcoholic Fatty Liver Disease. Pediatric Case Description of Three Submitted Sequential Biopsies
(Medical Univ Press, 2009-06-01)
Nonalcoholic fatty liver disease (NAFLD) is a clinical-pathological syndrome that encompasses a wide spectrum of morphologic alterations, ranging from simple hepatic steatosis to a more severe stage, known as nonalcoholic ...