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Mostrando ítems 21-30 de 1807
Interpopulation differences in parasite load and variable selective pressures on MHC genes in Ctenomys talarum
(Alliance Communications Group Division Allen Press, 2014-08)
We explore potential geographic variation in the pathogen-mediated selective pressures acting on Major Histocompatibility Complex (MHC) loci in the subterranean rodent Ctenomys talarum, evaluating the impact of differences ...
Mapping MHC Genes in River Buffalo
(Karger, 2014)
Females prefer good genes: MHC-associated mate choice in wild and captive tuco-tucos
(Academic Press Ltd - Elsevier Science Ltd, 2012-03)
The major histocompatibility complex (MHC) genes are one of the most suitable candidates for elucidating the genetic bases of mate choice in vertebrates, given the potential benefits in terms of immunocompetence that can ...
Design of a predicted MHC restricted short peptide immunodiagnostic and vaccine candidate for Fowl adenovirus C in chicken infection
(Biomedical Informatics, 2015)
Fowl adenoviruses (FAdVs) are the ethiologic agents of multiple pathologies in chicken. There are five different species of FAdVs grouped as FAdV-A, FAdV-B, FAdV-C, FAdV-D, and FAdV-E. It is of interest to develop ...
Pan-specific prediction of peptide-MHC Class I complex stability, a correlate of T cell immunogenicity
(American Association of Immunologists, 2016-07)
Binding of peptides to MHC class I (MHC-I) molecules is the most selective event in the processing and presentation of Ags to CTL, and insights into the mechanisms that govern peptide-MHC-I binding should facilitate our ...
The half life of TCR/pMHC interaction can modulate T cell activation in response to
(2007)
T cell activation results from T cell receptor (TCR) engagement by cognate peptide-MHC (pMHC) complexes on the surface of antigen presenting cells (APCs). We have previously shown that the half-life of the TCR/pMHC interaction ...
CIITA B-cell specific promoter suppression in MHC class II-silenced cell hybrids
(Springer-Verlag, 1998)
In this study, various sets of somatic cell hybrids,
generated by the fusion of epithelial cell lines
with B-lymphoblastoid cell lines, were analyzed for the
expression of major histocompatibility complex (MHC)
class ...
Improved methods for predicting peptide binding affinity to MHC class II molecules
(Wiley Blackwell Publishing, Inc, 2018-07)
Major histocompatibility complex class II (MHC-II) molecules are expressed on the surface of professional antigen-presenting cells where they display peptides to T helper cells, which orchestrate the onset and outcome of ...
Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification
(Springer, 2015-09)
A key event in the generation of a cellular response against malicious organisms through the endocytic pathway is binding of peptidic antigens by major histocompatibility complex class II (MHC class II) molecules. The bound ...