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Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma
(Faculdade de Medicina / USP, 2011)
OBJECTIVES: 1) To correlate the methylation status of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter to its gene and protein expression levels in glioblastoma and 2) to determine the most reliable method for ...
Methylation pattern of THBS1, GATA-4, and HIC1 in pediatric and adult patients infected with helicobacter pylori
(2013-10-01)
Background: Helicobacter pylori infection is usually acquired in childhood and persists into adulthood if untreated. The bacterium induces a chronic inflammatory response, which is associated with epigenetic alterations ...
Methylation pattern of THBS1, GATA-4, and HIC1 in pediatric and adult patients infected with helicobacter pylori
(2013-10-01)
Background: Helicobacter pylori infection is usually acquired in childhood and persists into adulthood if untreated. The bacterium induces a chronic inflammatory response, which is associated with epigenetic alterations ...
Epigenetic diversity of Saccharum spp. accessions assessed by methylation-sensitive amplification polymorphism (MSAP)
(Springer, 2020-05-24)
The epigenetic diversity of six genotype groups (commercial cultivars, S. officinarum, S. spontaneum, S. robustum, S. barberi, and Erianthus sp.) was assessed through methylation-sensitive amplification polymorphism (MSAP). ...
Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryo
(2020-08-02)
In early embryos, DNA methylation is remodelled to initiate the developmental program but for mostly unknown reasons, methylation marks are acquired unequally between embryonic and placental cells. To better understand ...
Reaction of 4,5-diamino-3-methyl-1-phenylpyrazole with 3-dimethylaminopropiophenones. Synthesis of new 4-aryl-6-methyl-8-phenyl-2,3-dihydropyrazolo[3,4-b]diazepines and 4-aryl-8-methyl-6-phenyl-2,3-dihydropyrazolo[4,3-b]diazepines
(HETERO CORPORATION, 1999-05)
New 4-Aryl-6-methyl-8-phenyl-2,3-dihydropyrazolo[3,4-b]diazepines and 4-aryl-8-methyl-6-phenyl-2,3-dihydropyrazolo[4,3-b]diazepines were obtained from the reaction of 4,5-diamino-3-methyl-1-phenylpyrazole 1 with one ...
Reaction of 4,5-diamino-3-methyl-1-phenylpyrazole with 3- dimethylaminopropiophenones. Synthesis of new 4-aryl-6-methyl-8-phenyl-2,3- dihydropyrazolo[3,4-b]diazepines and 4-aryl-8-methyl-6-phenyl-2,3- dihydropyrazolo[4,3-b]diazepines
(HeteroCorporation, 1999)
New 4-Aryl-6-methyl-8-phenyl-2,3-dihydropyrazolo[3,4-b]diazepines and 4- aryl-8-methyl-6-phenyl-2,3-dihydropyrazolo[4,3-b]diazepines were obtained from the reaction of 4,5-diamino-3-methyl-1-phenylpyrazole 1 with one ...
13C-NMR and theoretical studies of internal rotation in methylated anilines
(1998)
The conformational properties of ten ring-methylated N-methyl- and N,N-dimethylanilines have been studied using 13C-NMR chemical shifts and spin-lattice relaxation times in CDCl3, and semi-empirical (AM1) quantum-chemical ...
Recent patents of DNA methylation biomarkers in gastrointestinal oncology
(2010)
Gastrointestinal malignancies are among the most common malignancies worldwide. Advances in technology and treatment have improved diagnosis and monitoring of these tumors. As a consequence, identification of new biomarkers ...