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Link between metformin and the peroxisome proliferator-activated receptor γ pathway in the uterine tissue of hyperandrogenized prepubertal mice
(Elsevier Inc., 2011)
Chronic hyperandrogenism alters the peroxisome proliferator-activated receptor γ (PPARγ) pathway in the uterine tissue of prepubertal mice. The gene and protein expression of PPARγ is not modified, but the gene and protein ...
Effects of metformin on insulin resistance in obese and hyperandrogenic women Efecto de la metformina sobre la resistencia insulínica en mujeres obesas y obesas hiperandrogénicas
(1997)
Background: Metformin is a biguanide often used in obese diabetics that improves tissue sensitivity to insulin. Aim: To assess the effects of metformin on tissue insulin sensitivity in obese and hyperandrogenic women. ...
Metformin for the treatment of hyperandrogenism in adolescents with type 1 diabetes mellitus
(S. Karger AG, 2013)
© 2013 S. Karger AG, Basel.Background: A high prevalence of hyperandrogenism has been reported in women with type 1 diabetes (T1D). Metformin has been used as a therapeutic agent in patients with polycystic ovarian syndrome ...
The effects of maternal metformin treatment on late prenatal and early postnatal development of the offspring are modulated by sex
(2020)
Metformin is currently used to improve pregnancy outcome in women affected by polycystic ovary syndrome (PCOS) or diabetes. However, metformin may also be useful in pregnancies at risk of intrauterine growth restriction ...
Metformin and colorectal cancer
(Instituto de Histología y Embriología, 2021-08)
Colorectal cancer (CRC) is one of the main causes of cancer-related mortality in the developed world despite recent developments in detection and treatment. Several epidemiological studies indicate that metformin, a widely ...
Metformin in the treatment of polycystic ovary syndrome
(Bentham Science Publishers, 2008-08)
Polycystic ovary syndrome (PCOS) is one of the most frequent diseases that affects women in their reproductive age. The heterogeneity of PCOS makes not only the diagnosis but also the choice of an adequate treatment ...
Effects of metformin on QT and QTc interval dispersion of diabetic rats
(Arquivos Brasileiros CardiologiaSao PauloBrasil, 2008)