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Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI(3)K in mice
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Granulocyte-colony stimulating factor (G-CSF) is a current pharmacological approach to increase peripheral neutrophil counts after anti-tumor therapies. Pain is most relevant side effect of G-CSF in healthy volunteers and ...
ChIP-seq reveals a role for CrzA in the Aspergillus fumigatus high-osmolarity glycerol response (HOG) signalling pathway
(Wiley-Blackwell, 2014-11-01)
Aspergillus fumigatus is an opportunistic pathogen and allergen of mammals. Calcium signalling is essential for A. fumigatus pathogenicity and is regulated by the CrzA transcription factor. We used ChIP-seq (Chromatin ...
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling
(Nature Publishing Group, 2013-09)
In patients, non-proliferative disseminated tumour cells (DTCs) can persist in the bone marrow (BM) while other organs (such as lung) present growing metastasis. This suggested that the BM might be a metastasis ‘restrictive ...
Modificaciones anatomofisiológicas del sistema radical de plántulas de arroz (Oryza sativa L.), tratadas con aluminio
(Universidad de La Habana; Instituto Nacional de Ciencias Agrícolas, 2010)
El trabajo tuvo como objetivo fundamental determinar las modificaciones que provoca el Al en la anatomía y la fisiología del sistema radical de plántulas de arroz de dos variedades, mediante su interacción con diferentes ...
Role of adenosine transport in gestational diabetes-induced L-arginine transport and nitric oxide synthesis in human umbilical vein endothelium
(WILEY, 2004)
Gestational diabetes is associated with increased L-arginine transport and nitric oxide (NO) synthesis, and reduced adenosine transport in human umbilical vein endothelial cells (HUVEC). Adenosine increases endothelial ...
Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress
(Frontiers Research Foundation, 2019)
Interleukin-3 prevents neuronal death induced by amyloid peptide
(BIOMED CENTRAL LTD, 2007-10-03)
Background: Interleukin-3 (IL-3) is an important glycoprotein involved in regulating biological
responses such as cell proliferation, survival and differentiation. Its effects are mediated via
interaction with cell surface ...